Multimodal Sexual Dysfunction Intervention for Bone Marrow Transplant Survivors

This trial aims to improve sexual function, quality of life, and mood for individuals who have undergone a stem cell transplant and are experiencing distressing sexual dysfunction. It will compare two approaches: enhanced standard care, which includes educational materials, and a more involved multimodal intervention addressing sexual dysfunction through regular visits and potential specialist referrals. Suitable participants have had a stem cell transplant at least three months ago and are experiencing sexual difficulties affecting their well-being. As an unphased trial, this study provides a unique opportunity to explore innovative solutions for enhancing post-transplant sexual health and overall well-being.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that the combined approach to treating sexual problems in individuals who have undergone a stem cell transplant is safe and generally well-received. Earlier studies found that this treatment improved sexual satisfaction without causing major side effects. For example, one study reported that 94% of participants with sexual issues due to their treatment experienced positive results after using this approach.

Researchers are excited about these interventions for addressing sexual dysfunction in bone marrow transplant survivors because they offer a more comprehensive approach than current standard care. Unlike typical treatments that primarily provide educational material, the multimodal intervention involves personalized care with monthly visits from trained nurse practitioners. This approach allows for referrals to specialists for psychological issues, relationship discord, or concerns about malignancy, providing a tailored treatment plan. This holistic strategy aims to address the root causes of sexual dysfunction, potentially leading to more effective and sustainable results.

This trial will compare two approaches for addressing sexual dysfunction in bone marrow transplant survivors. The Enhanced Standard Care arm includes baseline data collection, informing the primary transplant clinician of sexual dysfunction, and providing American Cancer Society sexual educational material. The Multimodal Intervention arm involves monthly visits with trained study nurse practitioners and referrals to specialists if needed. Research has shown that a combined treatment approach, like the Multimodal Intervention, can improve sexual satisfaction for people who have had a stem cell transplant. Studies have found that this method, guided by trained healthcare professionals, leads to better sexual health and quality of life. Participants in these studies also felt less anxious or depressed. These findings suggest that the treatment could help with sexual problems in this group.¹²⁶⁷⁸