Heat Exposure for Occupational Stress

GP
Overseen ByGlen P Kenny, PhD
Age: 18+
Sex: Male
Trial Phase: Academic
Sponsor: University of Ottawa
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions. However, outdoor workers are typically exposed to dynamic conditions, with environmental heat often increasing progressively from morning to afternoon. Consequently, workers may experience substantially different patterns of heat exposure across the workday even when average daily heat exposure is equivalent. It remains unclear whether the temporal pattern of heat exposure influences the amount of work that can be performed or the physiological strain experienced during a workday. Understanding these responses is important for determining whether occupational heat-stress guidelines developed under constant laboratory conditions adequately protect workers exposed to progressively changing environmental conditions.

The primary objective of this study is to determine whether the temporal pattern of heat exposure influences work performed and physiological heat strain during a simulated occupational workday in healthy middle-aged and older men. Participants will complete two 9-hour simulated workdays consisting of a 4-hour morning work period, a 1-hour lunch break, and a 4-hour afternoon work period. During one trial, wet-bulb globe temperature (WBGT) will remain constant at 28°C throughout the workday, whereas during the other trial, WBGT will progressively increase from morning to afternoon to simulate the changing environmental conditions of a typical hot summer workday. Both trials will have the same mean daily WBGT of 28°C. Participants will perform moderate-intensity treadmill exercise, and measures including total work performed, core temperature, heart rate, and time to the initial stay-time threshold will be assessed to determine whether constant and progressively increasing heat exposures produce different physiological and work-performance responses across the workday.

Are You a Good Fit for This Trial?

This trial is for healthy middle-aged and older men. Participants should not have any health conditions that could put them at risk during heat exposure or moderate exercise.

Inclusion Criteria

Do not smoke or have been smoke free for at least 5 years
I am male.
English or French speaking
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Exclusion Criteria

Are regularly exposed to hot environments (e.g., occupational heat exposure)
Experience claustrophobia or discomfort in enclosed environments
Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness)
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What Are the Treatments Tested in This Trial?

Trial Overview

The study compares two types of simulated workdays: one with constant heat and another where the heat increases from morning to afternoon, both using treadmill exercise. The goal is to see how these patterns affect physical performance and body strain.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Progressively Increasing Heat ExposureExperimental Treatment1 Intervention
Group II: Constant Heat ExposureExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Ottawa

Lead Sponsor

Trials
231
Recruited
267,000+