10 Participants Needed

Indoor Temperature for Heat Stress

GP
Overseen ByGlen P Kenny, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to examine how indoor temperature affects older adults' body temperature and heart health, particularly when they wear extra clothing or engage in light activities. It tests whether the recommended indoor temperature of 26°C remains safe when combined with everyday actions and various clothing choices. Ideal participants are non-smokers aged 65-85 who speak English or French and have had stable high blood pressure or type 2 diabetes for at least five years. As an unphased trial, this study provides a unique opportunity to contribute to understanding how everyday environments impact health.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications. However, if you or the investigators think your medication use makes it inadvisable to participate, it might affect your eligibility.

What prior data suggests that this protocol is safe for older adults?

Research has shown that hot indoor environments can lead to heat stress, causing issues like heat exhaustion and heat stroke, particularly in older adults. The World Health Organization notes that heat stress is a major cause of weather-related deaths and can worsen existing health problems like heart disease and diabetes.

In this study, participants stay in rooms with temperatures of 26°C (78.8°F) while wearing light clothing, sometimes with extra layers or engaging in light exercise. Although 26°C is usually comfortable, added activity or clothing can increase heat stress. Research indicates that temperatures over 27°C (80.6°F) might raise the risk of health problems.

The study aims to understand how these conditions affect older adults. It does not involve any new medications or invasive procedures, so the main safety concerns involve monitoring for signs of heat-related discomfort or health issues. Researchers closely monitor participants for any negative effects from the heat.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to explore how different indoor temperature conditions impact heat stress. Unlike typical approaches that might focus on cooling devices like fans or air conditioning, this trial looks at how variations in clothing and physical activity at a constant temperature can affect the body's response to heat. By examining these everyday factors, the trial could uncover new strategies for managing heat stress in environments where temperature control is limited. This could lead to practical guidelines that help people stay comfortable and safe during hot weather without relying solely on external cooling methods.

What evidence suggests that this trial's simulated indoor temperature upper limit could be effective for managing heat stress in older adults?

This trial will evaluate the effects of different indoor temperature conditions on health and comfort. Research has shown that high indoor temperatures can harm health and comfort. Studies found that for every 1°C increase in indoor temperature, feelings of discomfort due to heat rise by 33%, and sleep problems increase by 24%. Warmer indoor spaces also correlate with health issues and lower overall well-being. To reduce these risks, experts recommend maintaining indoor temperatures at or below 26°C with 45% humidity. This setting is especially protective for older adults, who are more sensitive to heat. Participants in this trial will experience an indoor temperature maintained at 26°C and 45% relative humidity under various conditions, including with or without activity and with or without added clothing layers.13678

Who Is on the Research Team?

GK

Glen Kenny, PhD

Principal Investigator

University of Ottawa

Are You a Good Fit for This Trial?

This trial is for older adults aged between 65-85 years who are in good health. The study aims to understand how light clothing, added layers, and daily activities like light exercise affect their body temperature and heart strain at a set indoor temperature.

Inclusion Criteria

Non-smoking
I speak English or French.
I can understand and agree to the study's details.
See 1 more

Exclusion Criteria

Uncontrolled hypertension (BP >150 mmHg systolic or >95 mmHg diastolic in a sitting position)
Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable
Cardiac abnormalities identified during screening
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Exposure

Participants are exposed to indoor temperature upper limit of 26°C with varying clothing and activity levels to assess physiological and cognitive responses.

8 hours per session
Multiple sessions (in-person)

Follow-up

Participants are monitored for any delayed physiological or cognitive effects after exposure sessions.

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Simulated indoor temperature upper limit
Trial Overview The trial tests the effects of an indoor temperature limit of 26°C with varying conditions: resting or exercising in light or additional clothing. It seeks to determine if this standard temperature is safe during hot weather for older adults.
How Is the Trial Designed?
4Treatment groups
Experimental Treatment
Group I: Exposure to indoor temperature upper limit without physical activity and added clothing.Experimental Treatment1 Intervention
Group II: Exposure to indoor temperature upper limit with physical activity.Experimental Treatment1 Intervention
Group III: Exposure to indoor temperature upper limit with physical activity and added clothing.Experimental Treatment1 Intervention
Group IV: Exposure to indoor temperature upper limit with added clothing.Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Ottawa

Lead Sponsor

Trials
231
Recruited
267,000+

Citations

Review article Surviving indoor heat stress in United States ...High exposures to overheating during summer. Indoor Heat Index exceeded thresholds of 27 °C. Overheating was higher in the 30s′ low-rise site.
Indoor overheating: A review of vulnerabilities, causes, and ...The likelihood of exposure to overheated indoor environments is increasing as climate change is exacerbating the frequency and severity of hot weather and ...
Full article: Towards establishing evidence-based ...As the authors reported that “for an increase in 1ºC of indoor temperature, annoyance due to heat and sleep disturbance increased by 33% and 24% respectively.
Residential indoor temperatures and health: A scoping ...Most studies found warmer indoor temperatures were linked to adverse health, well-being, or thermal comfort outcomes.
Interaction between Indoor Occupational Heat Stress and ...They concluded that high temperatures, among other severe weather conditions, reduce production and that in such conditions the ex- isting cooling systems ...
Overview: Working in Outdoor and Indoor Heat EnvironmentsHeat stress can cause fine motor performance (like rebar tying or keyboarding) to deteriorate even in acclimatized individuals. Heat illness can contribute to ...
Heat and healthHeat stress is the leading cause of weather-related deaths and can exacerbate underlying illnesses including cardiovascular disease, diabetes, ...
Occupational Exposure to Heat and Hot EnvironmentsExposure to extreme heat can result in occupational illnesses caused by heat stress, including heat stroke, heat exhaustion, heat syncope, heat cramps, heat ...
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