Temperature Control for Heat Stress

GP
Overseen ByGlen P Kenny, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if maintaining indoor temperatures at or below 26°C helps older adults (ages 60-85) manage heat stress during extreme heat events. It examines whether this temperature limit can prevent health issues such as increased body temperature and heart strain over three days. One group will remain in an environment at 26°C continuously, while another will experience 34°C during the day and 26°C at night. The trial seeks non-smoking older adults who can speak English or French and have conditions like controlled high blood pressure or type 2 diabetes diagnosed at least five years ago. As an unphased trial, this study provides a unique opportunity to contribute to important research on managing heat stress in older adults.

Will I have to stop taking my current medications?

The trial protocol does not specify if you need to stop taking your current medications. However, if you or the investigators believe that your medication use or any changes in it make participation inadvisable, it may affect your eligibility.

What prior data suggests that this temperature control method is safe for older adults?

Research has shown that keeping indoor temperatures at or below 26°C can protect older adults from dangerous increases in body heat and heart strain during very hot weather. One study found no significant rise in body temperature or heart strain when the indoor temperature was maintained at 26°C, while higher temperatures led to increased strain.

The study aims to test whether maintaining a temperature of 26°C can prevent heat-related problems over several days. Previous research suggests that this temperature is safe and comfortable for older adults. The study simulates a heatwave over a few days to observe how participants' bodies respond to controlled heat conditions.

Overall, maintaining indoor temperatures at 26°C appears to be a safe and effective way to manage heat stress in older adults.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores how controlling indoor temperatures during heatwaves can impact health. Unlike standard methods that rely heavily on air conditioning, this trial tests two approaches: maintaining a consistent 26°C indoors and allowing daytime overheating with cooler nights. This investigation is unique because it aims to understand the health benefits of these temperature control methods, potentially offering more sustainable ways to manage heat stress without continuous air conditioning.

What evidence suggests that maintaining indoor temperature limits could be effective for reducing heat stress in older adults?

This trial will compare different indoor temperature conditions during heatwaves. Research has shown that maintaining indoor temperatures at 26°C (about 79°F) or lower can reduce physical stress during heatwaves. One study found that at 26°C, body temperature and heart strain did not significantly increase. Participants in one arm of this trial will experience this condition. Another arm will expose participants to higher daytime temperatures with cooler nighttime conditions. Previous studies found that heatwaves caused higher body temperatures at night and less sleep, suggesting that cooler indoor spaces can help older adults stay safer and more comfortable during extreme heat.12367

Are You a Good Fit for This Trial?

This trial is for older adults aged 60-85 who can safely undergo simulated heatwave conditions. The study aims to understand how indoor temperatures affect their body's response to heat and sleep quality over three days. Specific eligibility criteria are not provided, but typically participants must be in stable health without conditions that could interfere with the trial.

Inclusion Criteria

Non-smoking
Ability to provide informed consent
I have had high blood pressure or type 2 diabetes for over 5 years.

Exclusion Criteria

Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable
Uncontrolled hypertension - BP >150 mmHg systolic or >95 mmHg diastolic in a sitting position
Cardiac abnormalities identified during screening
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants are exposed to indoor temperature limits over three consecutive days (3 days, 2 nights) to assess the efficacy of proposed indoor temperature limits in mitigating increases in core temperature and cardiovascular strain.

3 days
Continuous monitoring during the 3-day exposure

Follow-up

Participants are monitored for any delayed effects of the heat exposure and to assess recovery.

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Simulated multi-day heatwave exposure
Trial Overview The study tests whether keeping indoor temperatures at or below 26°C during a simulated three-day heatwave helps reduce physical strain and improve sleep for older adults. Participants experience both constant recommended temperatures and higher daytime temperatures without cooling.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: Exposure to indoor temperature limits nighttime onlyExperimental Treatment1 Intervention
Group II: Exposure to indoor temperature limits daylongExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Ottawa

Lead Sponsor

Trials
231
Recruited
267,000+

Published Research Related to This Trial

The heat stress standard ISO 7243, based on the wet bulb globe temperature index (WBGT), is a reliable and valid method for assessing hot environments globally, but it has limitations regarding metabolic heat estimation and clothing effects.
To enhance its applicability, especially outdoors, the standard recommends using a WBGT equation that factors in solar absorptivity and introduces a 'clothed WBGT' to better account for clothing effects.
Heat stress standard ISO 7243 and its global application.Parsons, K.[2022]
In a study involving 26 firefighters, it was found that physiological heat strain, indicated by a higher core temperature, was significantly greater on the second day of back-to-back fire suppression work, despite no differences in hydration or heart rate between the two days.
Firefighters reported increased perceived exertion and thermal sensation on the second day, suggesting that even with full recovery, the demands of consecutive days of intense work can lead to greater heat strain and fatigue.
Heat Strain Is Exacerbated on the Second of Consecutive Days of Fire Suppression.Schlader, ZJ., Colburn, D., Hostler, D.[2022]
The study found that different heat stress assessment metrics significantly affect the estimated workability (WA) of labor in hot outdoor environments, with metrics like Wet Bulb Globe Temperature (WBGT) showing varying constraints based on workload and time of day.
Physiological models like Predicted Heat Strain (PHS) and Universal Thermal Climate Index (UTCI)-Fiala provide a more comprehensive understanding of cumulative physiological strain during extended work hours, suggesting that current WBGT standards may not adequately account for these factors.
Estimated work ability in warm outdoor environments depends on the chosen heat stress assessment metric.Bröde, P., Fiala, D., Lemke, B., et al.[2018]

Citations

Effects of Daylong Exposure to Indoor Overheating on ...Core temperature and cardiovascular strain were not appreciably altered following 8-h exposure to 26°C but increased progressively in conditions above this ...
Temperature Control for Heat Stress · Info for ParticipantsTrial Overview The study tests whether keeping indoor temperatures at or below 26°C during a simulated three-day heatwave helps reduce physical strain and ...
Impact of a simulated multiday heatwave on nocturnal ...In conclusion, the simulated heatwave resulted in higher overnight core temperature which was associated with reduced total sleep time. Behavioral ...
Effect of a Simulated Heat Wave on Physiological Strain ...We show for first time that a controlled simulated heat-wave increases workers' physiological strain and reduces labour productivity on the first day.
Impact of a simulated multiday heatwave on nocturnal ...This study investigated the impact of a multiday heatwave on nocturnal physiology, behavior, and sleep under controlled conditions with comprehensive ...
Effect of a Simulated Heat Wave on Physiological Strain ...Conclusions: Here, we show for first time that a controlled simulated heat-wave increases workers' physiological strain and reduces labour ...
Using Virtual Resources to Predict Heat Wave Outcomes ...Heatwaves have been linked to increased risk of mortality and morbidity and are projected to increase in frequency and intensity due to climate change.
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