1000 Participants NeededMy employer runs this trial

Data Analysis for Heart Failure

Recruiting at 5 trial locations
LA
Overseen ByLaura Alagna
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Northwestern University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to better understand heart failure by classifying it into different types to develop more personalized treatments. The study collects extensive data from heart images, blood tests, and health records to achieve this goal. It seeks participants who have heart failure or experience symptoms like shortness of breath or fatigue without a diagnosis. Those diagnosed with heart failure or experiencing symptoms that impact daily life without a known diagnosis may be suitable for this trial. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could lead to more personalized heart failure treatments.

Why are researchers excited about this trial?

Researchers are excited about the HeartShare trial because it aims to revolutionize how we understand and treat heart failure. Unlike current treatments, which often focus on symptom management, HeartShare combines advanced techniques like omics, deep phenotyping, and electronic health records to identify precise subtypes of heart failure. This approach could lead to highly personalized treatments, potentially improving outcomes for patients by targeting the condition more accurately. By integrating vast data sources, HeartShare may uncover new treatment targets that current therapies don't address.

Who Is on the Research Team?

SS

Sanjiv Shah, MD

Principal Investigator

Northwestern University

SS

Svati Shah, MD, MHS

Principal Investigator

Duke University

JB

Javed Butler, MPH, MBA

Principal Investigator

Baylor Scott and White Health

Are You a Good Fit for This Trial?

Inclusion Criteria

Age ≥30 years.
HF Inclusion Criteria (HeartShare Registry)
Prior diagnosis of HF in the EHR (any left ventricular ejection fraction).
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Data Collection

Participants undergo deep phenotyping, including heart ultrasounds, MRIs, and molecular data collection from blood samples

8-12 weeks

Follow-up

Participants are monitored for safety and effectiveness after data collection

4 weeks

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

Northwestern University

Lead Sponsor

Trials
1,674
Recruited
989,000+

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Trials
3,987
Recruited
47,860,000+

Massachusetts General Hospital

Collaborator

Trials
3,066
Recruited
13,430,000+

Brigham and Women's Hospital

Collaborator

Trials
1,694
Recruited
14,790,000+

Mayo Clinic

Collaborator

Trials
3,427
Recruited
3,221,000+

University of California, Davis

Collaborator

Trials
958
Recruited
4,816,000+

Wake Forest University Health Sciences

Collaborator

Trials
1,432
Recruited
2,506,000+

University of Pennsylvania

Collaborator

Trials
2,118
Recruited
45,270,000+