Meditation and Yogic Breathing for Healthy Adults

(SPANDHA Trial)

BS
Overseen ByBalachundhar Subramaniam, MD MPH
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Beth Israel Deaconess Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will examine whether meditation and yogic breathing can alter brain fluid movement and waste clearance in healthy adults. It will also evaluate the GLYMPHOMETER, a new external forehead-worn device designed to objectively measure changes in brain fluid movement and exchange during meditation.

Are You a Good Fit for This Trial?

This trial is for healthy adults. People with any health conditions or issues that could interfere with meditation, breathing exercises, or brain monitoring may not be able to participate.

Inclusion Criteria

Novice or Advanced as defined above
Fluent in English
I can travel to the BIDMC site twice within a week.
See 1 more

Exclusion Criteria

I have a history of heart or lung diseases.
I have a history of neurological or neurodegenerative disorders.
History of major psychiatric disorders (e.g., schizophrenia, bipolar disorder)
See 3 more

What Are the Treatments Tested in This Trial?

Interventions

  • Nadi Shuddhi
  • Shoonya Meditation

Trial Overview

The study tests whether specific yogic breathing (Nadi Shuddhi) and Shoonya Meditation can change how fluids move in the brain and help clear waste. It also checks if a new forehead device called GLYMPHOMETER can measure these changes during meditation.

How Is the Trial Designed?

2

Treatment groups

Active Control

Group I: Novice MeditatorsActive Control2 Interventions
Group II: Advanced MeditatorsActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Beth Israel Deaconess Medical Center

Lead Sponsor

Trials
872
Recruited
12,930,000+