60 Participants NeededMy employer runs this trial

Bioenhanced Eggs for Vitamin D Deficiency

(SCRAMBLE Trial)

KO
Overseen ByKimberly O'Brien, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Cornell University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this research is to evaluate if 1) consumption of vitamin D3- or 25(OH)D3-biofortified eggs will increase vitamin D and 25(OH)D status in young adults who consume these bioenhanced eggs, 2) to determine if the gut microbiome profile is associated with 25(OH)D or vitamin D status and 3) to evaluate possible changes in the gut microbiome following an 8-week supplementation period providing 5(OH)D- or vitamin D bioenhanced eggs.

Are You a Good Fit for This Trial?

This trial is for healthy adults who have low levels of vitamin D. People with certain health conditions or on medications that affect vitamin D may not be able to join.

Inclusion Criteria

Body mass index (BMI) between 18.5-27.0 kg/m2
I am a healthy adult.
No planned trip(s) to lower latitudes during the 8-week study
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Exclusion Criteria

I have digestive issues or take medicines that affect vitamin D absorption.
Planned trip(s) to lower latitudes during the 8-week study
BMI less than 18.5 or greater than 27.0 kg/m2
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What Are the Treatments Tested in This Trial?

Interventions

  • 25(OH)D3 bioenhanced eggs
  • Vitamin D3 bioenhanced eggs

Trial Overview

The study tests whether eating eggs enriched with either regular vitamin D3 or its active form, 25(OH)D3, can raise vitamin D levels and change gut bacteria in young adults over 8 weeks.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Vitamin D3 bioenhanced eggsExperimental Treatment1 Intervention
Group II: 25(OH)D3 bioenhanced eggsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Cornell University

Lead Sponsor

Trials
179
Recruited
14,090,000+