EDC Education for Male Infertility

(SEED Trial)

This trial explores how educating men about environmental toxins, known as endocrine-disrupting chemicals (EDCs), might affect their sperm quality and health choices. Participants will either receive an educational program (EDC Education Intervention) or undergo only urine and sperm testing. The goal is to determine if the education improves their understanding of environmental health and lifestyle decisions. Men with a low sperm count, who are in good health, and do not smoke might be suitable candidates for this study.

As an unphased trial, this study provides a unique opportunity to contribute to important research on environmental health and personal well-being.

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are using steroids or hormone replacement supplements.

Research has shown that certain chemicals, known as endocrine-disrupting chemicals (EDCs), can impact male fertility. These chemicals appear in everyday items like plastics and pesticides. Studies indicate that EDCs can lower sperm counts and affect sperm quality. However, this trial does not involve exposure to these chemicals. Instead, it focuses on educating participants about EDCs and how to avoid them. No known safety risks exist from receiving this education and lifestyle advice, indicating that the educational program is safe for participants.¹²³⁴⁵

Researchers are excited about the EDC Education Intervention for male infertility because it focuses on lifestyle changes and education, rather than just medical or surgical solutions. Current treatments often involve medication or surgery to address hormonal or anatomical issues. In contrast, this intervention aims to empower individuals through a lifestyle audit and educational program, potentially improving fertility by fostering healthier habits and awareness. This approach can be appealing as it encourages proactive, non-invasive steps toward fertility improvement.

Research has shown that certain chemicals, known as endocrine-disrupting chemicals (EDCs), can harm sperm quality. Studies have found that exposure to these chemicals can lead to lower sperm counts and less healthy sperm. This is significant because male infertility accounts for 40 to 50 percent of couples experiencing difficulty conceiving. In this trial, participants in the Education Intervention arm will receive the EDC Education Intervention, designed to improve sperm quality by teaching participants how to avoid these harmful chemicals. Previous research suggests that reducing exposure to EDCs could enhance male fertility.⁶⁷⁸⁹¹⁰