Hard Gum Chewing for Facial Appearance
(GUM-3D Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults. Twenty participants aged 20-40 years will undergo three-dimensional facial imaging (3dMD) at baseline (T0), after the 4-week chewing intervention (T1), and following a 4-5-week washout period (T2). Changes in facial soft-tissue morphology will be assessed using three-dimensional surface analysis, including heatmaps, regional surface displacement, and morphometric measurements. Secondary outcomes include self-reported muscle fatigue, soreness, adherence, and temporomandibular disorder (TMD) symptoms.
Who Is on the Research Team?
Flavio Uribe
Principal Investigator
UConn School of dental medicine
Thais Fernandes Poleti, PhD
Principal Investigator
UConn School of dental medicine
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants will perform a standardized hard-gum chewing protocol every other day for 4 weeks. Each session will last approximately 16 minutes and will follow a predefined chewing regimen. Three-dimensional facial images (3dMD) will be obtained at baseline (T0), immediately after the intervention period (T1), and after a 4-5-week washout period (T2) to evaluate changes in facial morphology.
Find a Clinic Near You
Who Is Running the Clinical Trial?
UConn Health
Lead Sponsor
Charles Burstone Foundation
Collaborator
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