60 Participants NeededMy employer runs this trial

OCT Devices for Eye Cancer

Recruiting at 6 trial locations
JF
DA
Overseen ByDavid Abramson, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Memorial Sloan Kettering Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to compare two devices used for optical coherence tomography (OCT), a scanning method that creates images of the back of the eye. These devices may help doctors better detect and monitor eye cancers. Participants will test the Heidelberg Spectralis OCT and the Intalight Dream OCT. This trial suits individuals with at least one eye tumor, either inside or on the surface, who can sit still for about two minutes. As an unphased trial, it offers a unique opportunity to advance eye cancer detection technology.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that these OCT devices are safe for eye cancer detection?

Previous studies have shown that both the Heidelberg Spectralis OCT and the Intalight Dream OCT are safe and easy to use for eye imaging. Research indicates that these devices are noninvasive, meaning they do not involve surgery or breaking the skin, which generally ensures patient safety.

For the Heidelberg Spectralis OCT, studies have confirmed its ability to consistently provide accurate results without causing harm. Similarly, the Intalight Dream OCT has received approval for use in the EU, indicating it meets safety standards there.

Both devices offer advanced imaging for the eye, enabling doctors to see and track tumors without causing negative side effects. This makes them promising options for those considering participation in a clinical trial for eye cancer monitoring.12345

Why are researchers excited about this trial?

Researchers are excited about the OCT devices for eye cancer because they offer a non-invasive way to capture detailed images of ocular tumors. Unlike traditional methods that might rely on biopsies or less precise imaging, the Heidelberg Spectralis OCT and Intalight Dream OCT provide high-resolution scans that can help in assessing tumor size and progression without surgery. These devices are particularly promising because they allow for real-time monitoring, potentially leading to more personalized and timely treatment adjustments for patients.

What evidence suggests that these OCT devices are effective for eye cancer?

This trial will evaluate the effectiveness of two OCT devices for detecting and monitoring eye cancers. Participants will be assessed using either the Heidelberg Spectralis OCT or the Intalight Dream OCT. Studies have shown that the Heidelberg Spectralis OCT provides detailed images, aiding doctors in identifying different types of eye tumors and improving visibility through cataracts. Meanwhile, the Intalight Dream OCT offers a wide view of the retina, which is crucial for locating eye tumors. Both devices have demonstrated manageable side effects, making them promising options for managing eye cancer.12345

Who Is on the Research Team?

JF

Jasmine Francis, MD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Are You a Good Fit for This Trial?

This trial is for adults (18 or older) who have a tumor in at least one eye, can keep their eyes open and still for about 2 minutes, can focus on a target, and whose pupils can dilate enough for imaging. People must not have any condition that blocks the view of the back of the eye.

Inclusion Criteria

I am 18 years old or older.
I have a tumor in or on the surface of at least one eye.
Pupils that can dilate up to at least 3 mm in the study eyes
See 4 more

Exclusion Criteria

Does not meet ALL of the above conditions

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Imaging

Participants undergo optical coherence tomography (OCT) imaging using two different devices to compare image quality and field of view

Up to 1 year

Follow-up

Participants are monitored for safety and effectiveness of imaging techniques after the initial imaging phase

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Heidelberg Spectralis OCT
  • Intalight Dream OCT

Trial Overview

The study compares two noninvasive OCT scanning devices—Intalight Dream OCT and Heidelberg Spectralis OCT—to see how well they image tumors in the eye. Each participant will be scanned with both devices.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Participants with Ocular TumorExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials
1,998
Recruited
602,000+

Intalight, Inc

Industry Sponsor

Citations

Anterior segment optical coherence tomography in ocular ...

This review shows that AS-OCT, as a noninvasive tool, has potential uses in the differential diagnosis of ocular surface tumours and simulating lesions.

OCT Devices for Eye Cancer

... Heidelberg Spectralis OCT and Intalight Dream OCT will have tolerable side effects & efficacy for patients with Ocular Neoplasms and Eye Cancer.

A Study Comparing Two Optical Coherence Tomography ...

The purpose of this study is to compare two devices used for optical coherence tomography (OCT). OCT is a noninvasive imaging (scanning) ...

Evaluation of optical coherence tomography (OCT) changes ...

This study uses OCT imaging to examine morphological changes at the chorioretinal interface of the choroidal melanoma biopsy site over time.

State-of-the-art commercial Spectral-Domain and Swept- ...

Reduced scattering by long wavelength. OCT imaging should result in better pene- tration of cataracts as compared to short wavelength OCT ...