AHF Checklist Implementation for Heart Failure

IS
Overseen ByIan Stiell, MD, MSc
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Ottawa Hospital Research Institute
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new checklist designed to help emergency doctors manage acute heart failure (AHF) more effectively. The checklist outlines clear steps for treating patients who arrive at the emergency room with sudden or worsening shortness of breath due to AHF. Some emergency departments will use this checklist, while others will continue with usual care to compare results. The study seeks patients who have recently experienced increased shortness of breath due to AHF. If successful, the checklist could be widely adopted across emergency departments to improve patient outcomes. As an unphased trial, this study offers patients the chance to contribute to potentially groundbreaking improvements in emergency care for AHF.

What prior data suggests that the CAEP AHF Checklist is safe for implementation in emergency departments?

Research has shown that the CAEP Acute Heart Failure (AHF) Best Practices Checklist aids healthcare providers in emergency rooms. It aims to enhance care for patients experiencing acute heart failure, a condition where the heart suddenly struggles to pump blood effectively.

This trial focuses on using a checklist rather than testing a new drug, resulting in minimal safety concerns. The checklist itself poses no direct negative effects. Instead, it seeks to make patient care more consistent and safer by reducing risks associated with uneven treatment.

Previous studies on similar guidelines have found that following structured plans can improve patient outcomes without introducing new health risks. Therefore, current evidence considers the checklist safe for use in emergency rooms.12345

Why are researchers excited about this trial?

Researchers are excited about the AHF Checklist Implementation because it aims to streamline and improve the emergency care process for heart failure patients. Unlike the usual care, which relies heavily on the clinician's discretion, this checklist offers a standardized approach that guides the assessment and treatment of acute heart failure. By incorporating implementation strategies like physician education and a smartphone app, it not only enhances clinical decision-making but also promotes consistent, high-quality care across different settings. This approach could lead to better patient outcomes and more efficient use of healthcare resources.

What evidence suggests that the CAEP AHF Checklist is effective for managing acute heart failure?

Studies have shown that patients with acute heart failure (AHF) who visit the emergency department (ED) due to breathing difficulties often face serious health risks or even death. To improve treatment in these situations, researchers developed the CAEP Acute Heart Failure Best Practices Checklist. In this trial, one group of participants will experience the implementation of this Checklist, which research suggests can lead to better patient outcomes, such as fewer deaths within 30 days and a lower chance of the patient's condition worsening after their first visit. Early results indicate that this organized approach helps doctors make quick and effective treatment decisions, which is crucial in emergencies. The Checklist provides clear guidance where specific instructions for handling AHF in the ED were previously missing.12356

Who Is on the Research Team?

IS

Ian Stiell, MD, MSc

Principal Investigator

Ottawa Hospital Research Institute

Are You a Good Fit for This Trial?

This trial is for adults who come to the emergency department with sudden heart failure symptoms, such as trouble breathing. There are no detailed inclusion or exclusion criteria listed, but it focuses on patients needing urgent care for acute heart failure.

Inclusion Criteria

Eligibility of patients reviewed by the blinded study Steering Committee
All resident and staff physicians managing patients with AHF in the ED including emergency, medicine, cardiology, and hospitalists are primary study participants
Both patients admitted to hospital and those discharged from the ED are included
See 1 more

Exclusion Criteria

I was diagnosed with a heart attack in the emergency department.
Patients considered terminal with death expected within 60 days
I do not have acute heart failure.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Implementation

Implementation of the CAEP Acute Heart Failure (AHF) Best Practices Checklist in emergency departments, including physician education sessions and use of a smartphone application

30 months

Transition

2-month transition period for hospitals to cross over from control to intervention

2 months

Follow-up

Participants are monitored for safety and effectiveness after implementation, including relapse and hospital admission rates

30 days

What Are the Treatments Tested in This Trial?

Interventions

  • CAEP Acute Heart Failure (AHF) Best Practices Checklist Implementation

Trial Overview

The study compares usual emergency care for acute heart failure with a new checklist designed to help doctors follow best practices. Four large hospitals will use this checklist to see if it improves patient management and outcomes.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Usual CareExperimental Treatment1 Intervention
Group II: CAEP AHF Checklist ImplementationExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ottawa Hospital Research Institute

Lead Sponsor

Trials
585
Recruited
3,283,000+

The Ottawa Hospital Academic Medical Association

Collaborator

Trials
24
Recruited
3,000+

Citations

CAEP Acute Heart Failure Best Practices Checklist - PMC

We created the CAEP Acute Heart Failure Best Practices Checklist to assist emergency physicians in Canada and elsewhere manage patients who present to the ...

Implementation of Acute Heart Failure Checklist

The primary outcome will be a composite of 3 clinical effectiveness variables: 1) regression accounting for the stepped wedge design.

CAEP Acute Heart Failure Best Practices Checklist

Acute heart failure is a common condition that frequently results in poor outcomes or death.1 2 o patients typically present to the ...

4.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/40897986/

CAEP Acute Heart Failure Best Practices Checklist

CAEP Acute Heart Failure Best Practices Checklist. Department of Emergency Medicine, Methodological and Implementation Research (MIR),

CAEP AHF Best Practices Checklist Implementation for ...

The primary outcome will be a composite of 3 clinical effectiveness variables: 1) Mortality <30 days, 2) Deterioration post index visit admission,

(PDF) CAEP Acute Heart Failure Best Practices Checklist

1. Overall approach (see specific conditions below) Treat underlying causes: · 2. Acute pulmonary edema Three treatments should be commenced, ...