Phono-Motor Therapy + Semantic Feature Analysis for Dyslexia

(AMT Trial)

This trial tests two types of therapy to determine which better aids reading difficulties caused by a stroke. Participants will receive either phono-motor therapy, which focuses on sounds and speech movements, or semantic feature analysis, which emphasizes understanding word meanings. The goal is to determine if matching the therapy to a person's specific type of reading impairment proves more effective. This trial suits those who had a stroke and now struggle with reading, provided they were fluent in English before the stroke and can still see and hear well. Participants will follow a thorough treatment schedule, with therapy sessions spread over several weeks. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could tailor therapies to individual needs.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that Phono-Motor Therapy (PMT) is generally well-tolerated. One study found it improves the use of sounds in language and enhances oral reading skills. No serious side effects were reported, suggesting safety for individuals with reading difficulties.

Semantic Feature Analysis (SFA) is also considered safe. Studies have demonstrated that it improves vocabulary and reading comprehension without major side effects. It has been successfully used with both children and adults.

Researchers are excited about this trial because it combines Phono-Motor Therapy and Semantic Feature Analysis in a way that is tailored to each individual's specific type of dyslexia. Unlike standard treatments that often use a one-size-fits-all approach, this trial uses computational modeling to predict the most effective therapy for each person's unique reading challenges. This personalized approach could lead to more effective and faster improvements in reading skills, making it a promising avenue for individuals with acquired dyslexia. By focusing on both phonological and semantic aspects of language processing, the trial aims to address the root causes of reading impairments more comprehensively than existing therapies.

Research shows that phono-motor therapy (PMT) can enhance sound processing and reading aloud. Some studies suggest PMT might outperform other methods for those with language difficulties. However, not everyone experiences improved reading comprehension, though some individuals do benefit. In this trial, participants in the model-matched group may receive PMT if it aligns with their computational model prediction.