50 Participants NeededMy employer runs this trial

Tyrvaya for Dry Eye Syndrome

BS
Overseen ByBridgitte Shen Lee, OD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Ocular Aesthetics, LLC dba Ocular Clinical Trials
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The objective of this study is to evaluate whether twice-daily use of Tyrvaya improves contact lens comfort in contact lens wearers.

Are You a Good Fit for This Trial?

This trial is for adults (18+) who wear daily disposable soft contact lenses at least 5 days a week, have dry eye symptoms and discomfort with their contacts, good vision with correction (20/40 or better), and are willing to use only the study nasal spray for dry eyes during the 3-month study.

Inclusion Criteria

My vision is 20/40 or better in both eyes with contact lenses.
Soft 1-day silicone hydrogel contact lens wearer (daily disposable only)
Contact Lens Dry Eye Questionnaire (CLDEQ)-8 scores ≥ 12
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Exclusion Criteria

I have used Tyrvaya in the past six months.
Condition or situation which in examiner's opinion may put subject at significant risk, confound study results, or interfere with participation
Currently wearing rigid gas permeable, scleral, hybrid, or reusable soft contact lenses
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What Are the Treatments Tested in This Trial?

Interventions

  • Tyrvaya

Trial Overview

The study tests whether using Tyrvaya (varenicline solution) nasal spray twice daily can improve comfort in people who experience dryness while wearing contact lenses. Participants will continue their usual lens routine but must not use other prescription dry eye treatments.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: TyrvayaExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ocular Aesthetics, LLC dba Ocular Clinical Trials

Lead Sponsor

Viatris Inc.

Industry Sponsor

Trials
11
Recruited
5,600+