Online Relapse Prevention Methods for Eating Disorders

(ORP Trial)

TE
CA
TE
Overseen ByTaylor E Penwell, B.A.
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Louisville
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests two online methods to help prevent relapses in individuals who have recently completed intensive treatment for eating disorders like anorexia or bulimia. One method uses imaginal exposure therapy, where participants face their fears through guided imagery, while the other focuses on writing and thinking exercises. The goal is to determine which method more effectively reduces symptoms and fears associated with eating disorders. Individuals who completed intensive treatment for an eating disorder within the last four months and continue to meet specific eating disorder criteria might be suitable for this study. As an unphased trial, this study offers a unique opportunity to explore innovative methods that could enhance recovery and prevent relapse.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that both imaginal exposure therapy and writing exercises are generally well-received by participants. Imaginal exposure therapy effectively reduces anxiety and behaviors related to eating disorders. Studies have not reported any major safety concerns, indicating that this treatment is safe for most people.

For the writing and thinking exercises, research has explored various expressive writing methods for those with eating disorders. Although participants sometimes felt sad after writing, no major safety issues were reported. This suggests that the writing exercises are safe for most individuals.

Both treatments have been studied without major negative effects, demonstrating they are generally safe for people to use.12345

Why are researchers excited about this trial?

Researchers are excited about these online relapse prevention methods for eating disorders because they offer innovative approaches compared to traditional therapy. For instance, the Imaginal Exposure Condition provides a unique way to confront fears and triggers by using mental imagery in a structured online setting, making it more accessible and less intimidating than in-person exposure therapy. Meanwhile, the Writing and Thinking Condition lets participants engage in introspective exercises that combine cognitive and emotional processing, which can enhance self-awareness and coping skills. These methods are particularly appealing because they can be done remotely, offering flexibility and convenience that standard in-person therapies often lack.

What evidence suggests that this trial's treatments could be effective for preventing relapse in eating disorders?

Research has shown that imaginal exposure therapy, one of the treatments in this trial, can effectively reduce anxiety and symptoms of eating disorders. This therapy helps individuals confront their fears about food and weight, making symptom management easier. Participants in this trial may also receive the writing and thinking intervention, which has been reviewed as helpful in reducing eating disorder symptoms by decreasing the tendency to avoid feelings. While cognitive behavioral therapy (CBT) is often regarded as highly effective for eating disorders, writing therapy offers a promising alternative with positive results. Both treatments in this trial aim to address core fears and improve emotional processing, which are crucial for managing eating disorders.56789

Who Is on the Research Team?

CA

Cheri A Levinson, PhD

Principal Investigator

University of Louisville

Are You a Good Fit for This Trial?

This trial is for adults over 18 who've recently left intensive treatment for eating disorders like anorexia or bulimia. It's not suitable for those with severe mental health issues, medical instability, or anyone discharged from care over a month ago.

Inclusion Criteria

I was discharged from an intensive care program within the last month.
I am over 18 years old.
I have been diagnosed with anorexia, atypical anorexia, or bulimia.

Exclusion Criteria

You do not have anorexia, atypical anorexia, or bulimia.
I was discharged from intensive treatment over a month ago.
high and active suicidality, psychosis, mania, or medical compromised status will be excluded, as these comorbidities would make it difficult to complete study procedures

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo either imaginal exposure therapy or a writing and thinking intervention, with one phone session followed by four online sessions over one month

4 weeks
1 phone session, 4 online sessions

Follow-up

Participants are monitored for relapse and changes in eating disorder symptoms, fear extinction, and other psychological measures

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Imaginal Exposure Condition
  • Writing and Thinking Condition
Trial Overview The study compares two relapse-prevention methods post-eating disorder treatment: imaginal exposure therapy and a writing/thinking task. It aims to see which better prevents relapse and improves symptoms and fears related to eating disorders.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Imaginal Exposure ConditionExperimental Treatment1 Intervention
Group II: Writing and Thinking ConditionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Louisville

Lead Sponsor

Trials
353
Recruited
76,400+

National Institute of Mental Health (NIMH)

Collaborator

Trials
3,007
Recruited
2,852,000+

King's College London

Collaborator

Trials
772
Recruited
26,130,000+

Citations

1.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/32794449/
Eating disorder symptoms and core eating disorder fears ...Online imaginal exposure is a feasible treatment for EDs and is associated with decreases in core ED symptomatology, which are comparable in magnitude to ...
Facing Eating Disorder Fears: An Open Trial Adapting ...Imaginal and in vivo exposure for eating disorders was a feasible intervention. •. Eating disorder symptoms and fears decreased from pretreatment to follow-up.
Study Details | NCT03712748 | Online Imaginal ExposureIn this case study, the investigators found that imaginal exposure therapy was effective at reducing anxiety and eating disorder behaviors. Imaginal exposure ...
A pilot randomized control trial of online exposure for eating ...We will test the efficacy of the imaginal exposure treatment in reducing ED symptoms and fears of food and weight gain, and whether fear learning is a ...
Studies on Anorexia, Bulimia and ObesityThese findings suggest that imaginal exposure response techniques are potentially successful to target core phobic fears and anxiety in AN and ...
Study Details | NCT03712748 | Online Imaginal ExposureIn this case study, the investigators found that imaginal exposure therapy was effective at reducing anxiety and eating disorder behaviors. Imaginal exposure ...
7.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/36736788/
An examination of eating disorder fears in imaginal ...Conclusions: Imaginal exposure scripts contained a large number of fears related to food, weight/shape, judgment, and loss of control, among ...
State mechanisms of change in eating disorder symptoms ...Eating disorder symptoms and core eating disorder fears decrease during online imaginal exposure therapy for eating disorders. J. Affect ...
IMAGINAL EXPOSURE FOR DISORDERED EATING ...Compulsive and/or safety behaviors such as body checking, calorie counting, or ritualized eating behaviors also serve as attempts to prevent feared outcomes.
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