Coordinated Specialty Care for Psychosis
(AC-EPINET Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores two methods of delivering Coordinated Specialty Care (CSC) for individuals with psychosis. One group receives care in a clinic, while the other receives care through telehealth (online or phone-based services). The trial aims to determine which method better engages patients and improves their health outcomes over 12 months. Individuals who have experienced a non-affective or affective psychotic disorder (such as schizophrenia or bipolar disorder with psychotic features) within the last five years and can attend one of six specific clinical programs may be suitable candidates. As an unphased trial, this study provides a unique opportunity to contribute to innovative care methods for psychosis.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this protocol is safe for treating psychosis?
Research shows that Coordinated Specialty Care (CSC) is a safe and effective early treatment for individuals experiencing their first episode of psychosis. Studies have found that CSC reduces hospital visits and enhances success in school and work. It also alleviates symptoms and improves overall well-being.
This trial tests a telehealth version of CSC, which gained popularity during the pandemic. Research on telehealth CSC suggests it can be effective and implemented successfully. Although specific safety details for the telehealth version are not highlighted, the traditional CSC model is known for its safety, indicating the telehealth version is likely safe as well.
Since this trial is not in its early stages, major safety issues have likely been addressed. Participants can feel reassured knowing CSC has a strong history of safety and effectiveness.12345Why are researchers excited about this trial?
Researchers are excited about the Coordinated Specialty Care (CSC) approaches for psychosis because they offer innovative ways to deliver mental health treatment. Unlike traditional in-person methods, the CSC-TH arm utilizes telehealth to provide care, making it more accessible for people who might struggle to get to a clinic. This could be a game-changer for those in remote areas or with transportation challenges. Both CSC models aim to offer a comprehensive treatment plan that integrates various services, potentially leading to more effective management of psychosis symptoms compared to conventional options.
What evidence suggests that this trial's treatments could be effective for psychosis?
Studies have shown that Coordinated Specialty Care (CSC) effectively supports individuals experiencing their first episode of psychosis. Research indicates that CSC can reduce hospital visits, improve job and school success, and decrease symptoms. In this trial, participants will receive either the standard clinic-based CSC model (CSC-SD) or the telehealth-based CSC model (CSC-TH). CSC-TH, the online version, offers the same benefits but is delivered over the internet, making access to care more convenient. Both standard CSC and CSC-TH aim to help individuals live healthier, more stable lives.13678
Who Is on the Research Team?
Alan Breier
Principal Investigator
Indiana Univeristy
Are You a Good Fit for This Trial?
This trial is for young individuals aged 16-35 who have recently been diagnosed with certain mental health conditions, including schizophrenia and bipolar disorder with psychotic features. Participants must be new to one of the six clinical programs, able to consent, and commit to the study schedule.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either telehealth-based or standard clinic-based CSC model treatment for 12 months
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Coordinated Specialty Care (CSC)
Coordinated Specialty Care (CSC) is already approved in United States, European Union for the following indications:
- First episode psychosis
- Psychotic disorders
- First episode psychosis
- Psychotic disorders
Find a Clinic Near You
Who Is Running the Clinical Trial?
Indiana University
Lead Sponsor
Vanderbilt University
Collaborator
University of Rochester
Collaborator
University of Michigan
Collaborator
Yale University
Collaborator
Ohio State University
Collaborator
Tulane University
Collaborator
National Institute of Mental Health (NIMH)
Collaborator
Northwestern University
Collaborator