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Online Self-Help for Depression

(SOS-Depression Trial)

Not yet recruiting at 1 trial location
LB
Overseen ByLucinda B Leung, MD, PhD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, Los Angeles
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Depression is disabling and affects one in five Veterans. VA's Primary Care-Mental health Integration (PCMHI) enables specialists to support medication treatment in primary care, but timely and sufficient access to psychotherapy is unattainable despite Veteran preference for psychotherapy. This study aims to close the gap in psychotherapy access for VA primary care patients with depression by adapting PCMHI collaborative care models to improve uptake of peer-supported computerized cognitive behavioral therapy (cCBT).

Are You a Good Fit for This Trial?

This trial is for veterans who are patients in VA primary care and have depression. Participants should be able to use online tools and want help managing their depression. People with conditions that would make participation unsafe or unsuitable may not be eligible.

Inclusion Criteria

Must be enrolled in the VHA and currently receiving primary care services at VA Los Angeles or San Diego
Have access to computer (mobile or desktop), internet, telephone, and email
Able to read English text on a computer screen
See 1 more

Exclusion Criteria

Have other serious mental illness (e.g. bipolar disorder, psychosis)
Have moderate-high suicide risk (e.g. suicide flag) or active suicidality
Have medical disorder that would prevent or interfere with participation (e.g. dementia/cognitive impairment, terminal illness)

What Are the Treatments Tested in This Trial?

Interventions

  • Supported Online Self-help for Depression (SOS-Depression)

Trial Overview

The study compares two approaches: usual care enhanced with extra support, versus a supported online self-help program using computerized cognitive behavioral therapy (cCBT) for depression, guided by peers.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Supported Online Self-help for Depression (SOS-Depression)Experimental Treatment1 Intervention
Group II: Enhanced Usual Care (EUC)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, Los Angeles

Lead Sponsor

Trials
1,594
Recruited
10,430,000+

San Diego Veterans Healthcare System

Collaborator

Trials
38
Recruited
5,500+

VA Greater Los Angeles Healthcare System

Collaborator

Trials
53
Recruited
8,700+

Congressionally Directed Medical Research Programs

Collaborator

Trials
59
Recruited
10,600+

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