20 Participants Needed

Music Therapy for Depression

(AMEND Trial)

SM
Overseen ByShantelena Mouzon
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Icahn School of Medicine at Mount Sinai
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how music therapy might help manage depression. Participants will attend 11 sessions of music therapy, with some also attending recitals to interact with performers. The aim is to determine if these experiences can improve mood and social interactions. Individuals experiencing symptoms of depression, as noted by a parent, might be suitable for this trial. As an unphased study, this trial provides a unique opportunity to explore innovative approaches to managing depression through music therapy.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to ask the study organizers for more details.

What prior data suggests that music therapy is safe for treating depression?

Research shows that music therapy is generally safe for people with depression. One study found that music therapy reduced depression symptoms more effectively than not using it. Although the quality of research on music therapy varies, no major reports of harm or serious side effects have emerged. In simple terms, music therapy is well-tolerated, meaning most people can use it without problems. Participants in these studies usually experience mood improvements without negative effects. Therefore, considering a trial with music therapy appears to be a safe choice based on current research.12345

Why are researchers excited about this trial?

Researchers are excited about music therapy for depression because it offers a non-pharmaceutical option that can be both engaging and therapeutic. Unlike typical antidepressants, which can take weeks to show effects and might have side effects, music therapy focuses on enhancing emotional expression and mood regulation through personalized music sessions. This approach is unique because it combines the psychological benefits of music with structured therapeutic techniques, potentially providing relief in a more holistic and accessible way.

What evidence suggests that music therapy could be an effective treatment for depression?

Studies have shown that music therapy can effectively reduce symptoms of depression. Research indicates that it is more effective than no treatment in alleviating these symptoms. For example, one study found that music therapy significantly decreased depression levels, meaning participants experienced a noticeable mood improvement. Another study highlighted that active music therapy, especially sessions lasting more than 60 minutes per week, proved particularly effective. These findings suggest that music therapy could be a helpful treatment option for those struggling with depression.13467

Who Is on the Research Team?

JV

Joanne V Loewy, D.A., LCAT, MT-BC

Principal Investigator

Icahn School of Medicine at Mount Sinai

Are You a Good Fit for This Trial?

This trial is for children with depression or symptoms of it, as confirmed in writing by a parent. There are no specific exclusion criteria listed, so it appears open to all kids who meet the inclusion condition.

Inclusion Criteria

Must indicate depression or symptoms thereof by parent in writing

Exclusion Criteria

Not applicable.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 11 weekly music therapy sessions and engage in recitals and discussions at the Third Street School Music Settlement

11 weeks
11 visits (in-person)

Follow-up

Participants are monitored for changes in depression and resilience using CDI2S and CD-RISC10 scales

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Music Therapy
Trial Overview The study tests music therapy's impact on depression and anxiety. Participants will attend 11 music therapy sessions, some followed by recitals at Third Street School Music Settlement to explore the effects of performance and creativity on their mental health.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Placebo Group
Group I: MusicExperimental Treatment1 Intervention
Group II: ControlPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Icahn School of Medicine at Mount Sinai

Lead Sponsor

Trials
933
Recruited
579,000+

Third Street Music School

Collaborator

Citations

Effects of group music therapy on depressive symptoms in ...Results suggest, that participants in GMT showed greater reductions in momentary depression, but not in self- and observer-rated depression ...
Comparative effects of music interventions on depression ...Although active music therapy >60 minutes/week by music therapist is the most effective intervention to alleviate depression in older adults.
Music therapy for patients with depression: systematic ...Music therapy was significantly more effective than controls in reducing depressive symptoms (standardised mean difference (SMD) −0.97 [95% CI: ...
4.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/40922518/
Music therapy for patients with depressionResults: Music therapy was significantly more effective than controls in reducing depressive symptoms (standardised mean difference (SMD) ...
Efficacy of music therapy for depressive symptoms in ...Pooled estimates showed significant reductions in depressive symptoms as measured by SDS (SMD = −1.19, 95% CI: −1.56 to −0.82; p < 0.001), SCL- ...
The safety and effectiveness of music medicine as ...The methodological quality of SRs/MAs of music as an intervention in depression is generally poor, and the level of evidence is generally low.
The Transformative Power of Music in Mental Well-BeingA 2022 review and meta-analysis of music therapy found an overall beneficial effect on stress-related outcomes. Moreover, music can be used ...
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