Pre-visit Prompts for Deprescribing

JC
Overseen ByJulie C Lauffenburger, PharmD, PhD
Age: 65+
Sex: Any
Trial Phase: Academic
Sponsor: Brigham and Women's Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how pre-visit prompts can assist patients in discussing the possibility of stopping or reducing certain medications with their doctors. It focuses on individuals aged 65 and older who have upcoming appointments at specific clinics and are using medications that may no longer be necessary. Patients may qualify if they have diabetes, high blood pressure, smoke, or have high cholesterol, and are currently using medications identified as high-risk for older adults. The trial will compare patients who receive these prompts with those who follow their usual care routine. As an unphased trial, this study provides a unique opportunity for patients to actively engage in improving healthcare conversations and potentially reduce unnecessary medication use.

What prior data suggests that these pre-visit prompts are safe for patients?

Research shows that reducing unnecessary medications, known as deprescribing, can enhance safety for older adults. Studies indicate it lowers the number of medications taken and reduces harmful reactions to drugs, known as adverse drug events (ADEs). This is crucial for people over 65, who often take many medications.

In this trial, researchers use pre-visit prompts to encourage patients to discuss their medications with their doctors. These prompts are not medications and therefore do not have side effects like drugs. Instead, they assist patients and doctors in deciding if some medications can be stopped or reduced due to potential harm or lack of necessity.

In summary, while the prompts are not a drug treatment, they promote safer medication use, which research has shown benefits older adults.12345

Why are researchers excited about this trial?

Researchers are excited about the pre-visit prompts because they offer a proactive approach to deprescribing. Unlike standard care, which relies on routine visits and discussions initiated by healthcare providers, this method empowers patients to engage directly in conversations about their medications. By providing a prompt and a handout before visits, patients are encouraged to discuss their medication use with primary care providers. This approach could lead to more personalized and safer medication plans, potentially reducing unnecessary drug use and associated side effects.

What evidence suggests that pre-visit prompts are effective for deprescribing?

Studies have shown that reducing unnecessary medications for older adults can improve their health and safety. By cutting down on potentially harmful drugs, these interventions lead to better health outcomes. Research indicates that when patients discuss their medications with doctors, they are more likely to stop or reduce those they don't need. This process, called deprescribing, aims to use medications wisely and improve health without causing harm. In this trial, some participants will receive pre-visit prompts, which have increased the chances of discussing and successfully reducing unnecessary medications.678910

Are You a Good Fit for This Trial?

This trial is for people aged 65 or older who have an upcoming primary care visit at a BWH clinic. They must either be eligible to start statins for heart health or currently take medications considered risky for older adults. People with certain medication allergies cannot join.

Inclusion Criteria

I have an upcoming appointment with a primary care physician at a participating clinic.
I am 65 years old or older.
I am 65-75, have a heart risk factor, and am not currently taking a statin.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Intervention

Participants receive a pre-visit prompt with information about the medication target prior to their PCP appointment

1 day
1 visit (in-person)

Follow-up

Participants are monitored for completion of medication prescribing/deprescribing target within 60 days after the PCP visit

8 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Pre-visit prompts

Trial Overview

The study tests if sending patients a pre-visit prompt about their medications helps them and their doctors make safer choices, like stopping risky drugs or starting helpful ones. Patients are randomly assigned to get the prompt or usual care.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Pre-visit patient promptsExperimental Treatment1 Intervention
Group II: Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Brigham and Women's Hospital

Lead Sponsor

Trials
1,694
Recruited
14,790,000+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+

University of Southern California

Collaborator

Trials
956
Recruited
1,609,000+

Citations

Interventions to Deprescribe Potentially Inappropriate ... - PMC

The goal of this study was to conduct a focused narrative review of the deprescribing literature through an IS lens - to determine the extent to which ...

Patient Barriers to and Enablers of Deprescribing

Deprescribing can help optimize medication use and improve functioning in older adults by reducing potentially harmful polypharmacy. ... ... As ...

Deprescribing practices in Canada: A scoping review - PMC

Patient-specific deprescribing interventions aimed at reducing polypharmacy improve longevity without adversely affecting health outcomes. Within the last ...

Deprescribing interventions in older adults: An overview of ...

The objective of this overview of systematic reviews was to summarize the review evidence for deprescribing interventions in older adults.

Implementation considerations of deprescribing interventions

This review summarizes (1) the process of deprescribing and conceptual models and tools that have been developed to facilitate deprescribing, (2) ...

6.

deprescribing.org

deprescribing.org/

Deprescribing.org - Optimizing Medication Use

Deprescribing research and guidelines support healthcare providers and patients in reducing or stopping medications that may be harmful or no longer needed.

WebMD's Drugs, Vitamins & Supplements Database

Find detailed information on prescription drugs, OTC medications, vitamins and dietary supplements, including their uses, side effects, and interactions.

Billing for Supervised Medication Deprescribing Services ...

Developing, reviewing, and revising a care plan for deprescribing, including the tapering schedule, target doses, and contingency plans for ...

Medication - FHIR v4.0.1

This resource is primarily used for the identification and definition of a medication for the purposes of prescribing, dispensing, and administering a ...

Medicines A to Z

Find out how your medicine works, how and when to take it, possible side effects and answers to your common questions.