192 Participants NeededMy employer runs this trial

CSPS Toothpaste for Tooth Sensitivity

HR
Overseen ByHaleon Response Center
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: HALEON

What You Need to Know Before You Apply

What is the purpose of this trial?

The aim of this study is to demonstrate the clinical efficacy of the Test Toothpaste containing Calcium Sodium Phosphosilicate (CSPS) in reducing Dentin Hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium fluoride Reference Toothpaste, after 8 Weeks of twice daily use.

Who Is on the Research Team?

CR

C. R. Goyal

Principal Investigator

All Sum Research Center Ltd.

Are You a Good Fit for This Trial?

This trial is for adults who have sensitive teeth (dentine hypersensitivity). Participants should generally be healthy and have noticeable tooth sensitivity. People with certain dental conditions or recent dental treatments may not be able to join.

Inclusion Criteria

Participant is willing and able to comply with the study visit schedule, product usage instructions, lifestyle restrictions, and other study procedures
Clinical examiner will select two 'test teeth' meeting tactile threshold and Schiff sensitivity score criteria at both Screening and Baseline
Participant is in good general, oral and mental health with no clinically significant or relevant abnormalities in self-reported medical history or oral examination impacting safety, wellbeing, study outcomes, or ability to follow study requirements
See 5 more

Exclusion Criteria

Participant with recent history (within last year) of alcohol or substance abuse
Participant previously enrolled in this study
Participant with known or suspected intolerance or hypersensitivity to the study products or ingredients
See 25 more

What Are the Treatments Tested in This Trial?

Trial Overview

The study compares a new toothpaste containing Calcium Sodium Phosphosilicate (CSPS) to a regular fluoride toothpaste, both used twice daily for 8 weeks, to see which works better at reducing tooth sensitivity.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Test ToothpasteExperimental Treatment1 Intervention
Group II: Reference ToothpastePlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

HALEON

Lead Sponsor

Trials
40
Recruited
6,000+