Music-based Intervention for Dementia

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Duke University
Must be taking: Psychotropic, Sedatives, Anti-dementia, Opioids

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a music-based program to determine if it can improve the relationships between people with dementia and their family caregivers. The program involves creating a playlist of favorite music for the person with dementia, using their preferred songs and artists. It suits individuals diagnosed with dementia who have recently felt dissatisfied with their caregiver relationship. Those experiencing memory problems and who enjoy music might consider this trial.

As an unphased trial, it provides a unique opportunity to explore how music can enhance relationships and well-being.

What prior data suggests that this music-based intervention is safe for individuals with dementia?

Research has shown that music therapy is safe for people with dementia and does not cause side effects. It is also more affordable than medication. Music therapy can reduce restlessness and anxiety in people with dementia and might improve memory and thinking skills. Overall, music therapy is well-received and beneficial for those living with dementia.12345

Why are researchers excited about this trial?

Researchers are excited about the Dyadic Music-based Intervention (MBI) for dementia because it offers a unique, personalized approach that differs from traditional treatments like medication and cognitive therapies. Unlike these standard options, the MBI involves creating a custom playlist of familiar and preferred music for each person living with dementia, engaging them emotionally and cognitively. This method aims to enhance mood, stimulate memory, and improve the quality of interactions between individuals with dementia and their caregivers, all through the power of music. By tapping into the emotional and cognitive benefits of music, this intervention could potentially provide a non-invasive and enjoyable way to manage dementia symptoms.

What evidence suggests that this trial's treatments could be effective for dementia?

Research has shown that music can help people with dementia by lifting their mood and easing anxiety. In this trial, participants will engage in either a Dyadic Music-based Intervention (MBI) or a Reminiscence Activity. Studies have found that listening to favorite or familiar songs can evoke memories and emotions, enhancing interaction and communication between people with dementia and their caregivers. Early findings also suggest that music can reduce stress for both individuals with dementia and their family members. Although more research is needed, the positive effects of music on mood and social interaction are encouraging.678910

Who Is on the Research Team?

DP

Darina Petrovsky

Principal Investigator

Duke University

Are You a Good Fit for This Trial?

This trial is for people living with dementia and their family caregivers who are willing to participate together. Specific inclusion or exclusion criteria were not listed, but both the person with dementia and their care partner must be able to join as a pair.

Inclusion Criteria

Care partner or person living with dementia (PLWD) reporting current or past (8-12 months) dissatisfaction with relationship score of 3 or less on relationship satisfaction measure
Care partner self-identifies as primary care partner
Care partner must reside with patient
See 7 more

Exclusion Criteria

Patient with hearing impairment defined as inability to hear normal speaking voice at 1.5 feet
Patient with planned transition to residential or institutional care setting in less than 3 months
Patient currently enrolled in interventional clinical trial for PLWD aimed to improve relationship quality
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a dyadic music-based intervention with weekly sessions for 6 weeks

6 weeks
6 visits (virtual)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Dyadic Music-based Intervention (MBI)
  • Reminiscence Activity

Trial Overview

The study is testing whether a structured music-based activity done by both the person with dementia and their caregiver is practical and acceptable, compared to a reminiscence (memory-sharing) activity.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Persons Living With Dementia (PLWD) - Caregiver DyadsExperimental Treatment1 Intervention
Group II: Reminiscence activityPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Duke University

Lead Sponsor

Trials
2,495
Recruited
5,912,000+

National Institutes of Health (NIH)

Collaborator

Trials
2,896
Recruited
8,053,000+

National Center for Complementary and Integrative Health (NCCIH)

Collaborator

Trials
886
Recruited
677,000+

Citations

What is Dementia? Symptoms, Causes & Treatment

Dementia is a general term for loss of memory, language, problem-solving and other thinking abilities that are severe enough to interfere with daily life.

Dementia

WHO fact sheet on dementia providing key facts and information on signs and symptoms, rates, risk factors, social and economic impacts, ...

Alzheimer's disease - Symptoms and causes

Understand more about this brain disease that is the most common cause of dementia. Also learn about new tests and medicines.

What Is Alzheimer's Disease? | National Institute on Aging

Alzheimer's disease is the most common form of dementia, a brain disorder that slowly destroys a person's memory and thinking skills. It is ...

What Is Dementia?

Learn about the symptoms of dementia and the different neurodegenerative diseases that cause dementia.

The effect of music therapy on cognitive functions in ...

The findings of this review suggest that music therapy could have a positive impact on cognitive functions in patients with AD.

The Effects of Music Therapy on Agitation and Anxiety in ...

In patients with mild to moderate dementia, is music therapy an effective non -pharmacologic intervention to reduce agitation and anxiety?

MUSIC THERAPY AND DEMENTIA - RUcore

music therapy is safe because it does not have any side effects. It is a cost-effective alternative to the pharmacological approach

Music-based therapy may benefit people living with dementia

A new Cochrane review has found evidence that music-based therapy may benefit people living with dementia, particularly by improving symptoms ...

Music Therapy and its Effects on Alzheimer's Disease

Evidence shows that music therapy reduces aggression, agitation, and anxiety, significantly improving BPSD symptoms. It also enhances in ...