Vagal Nerve Stimulation for Post-Surgical Recovery

(tVNS Trial)

This trial explores whether a non-invasive treatment called transcutaneous vagal nerve stimulation (tcVNS) can enhance recovery after surgery. Researchers aim to determine if this method can help patients wake up more smoothly from anesthesia, expedite discharge from the recovery room, and reduce post-surgery delirium and depression. The trial includes two groups: one receiving the actual tcVNS treatment and the other receiving a sham (fake) version for comparison. This trial may suit those undergoing lumbar surgery for back issues like degenerative disc disease or spinal stenosis. As an unphased trial, it offers patients the chance to contribute to innovative research that could improve surgical recovery.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that transcutaneous vagal nerve stimulation (tcVNS) is generally safe, with a low risk of serious side effects. Studies have found that tcVNS usually causes only mild and temporary issues, such as earaches, headaches, or a tingling sensation. These effects are not serious and do not last long. In past studies, no serious adverse events were reported. This suggests that tcVNS is well-tolerated and can be safely used in various situations, including recovery after surgery.¹²³⁴⁵

Transcutaneous vagal nerve stimulation (tcVNS) is unique because it uses a non-invasive method to potentially enhance post-surgical recovery by stimulating the vagus nerve through the skin. Unlike traditional treatments that might involve medication with various side effects, tcVNS offers a novel way to promote healing and reduce inflammation without drugs. Researchers are excited about this approach because it could provide a safer, more targeted way to speed up recovery times and improve overall patient outcomes after surgery.

Research has shown that transcutaneous vagal nerve stimulation (tcVNS) may enhance recovery after surgery. In this trial, participants will receive either tcVNS or a sham tcVNS as a control. Studies suggest that tcVNS can help manage pain, reduce swelling, and lower the risk of long-term pain post-surgery. Specifically, patients who received tcVNS reported better sleep and faster recovery of cognitive skills. Additionally, tcVNS seems to aid in more effective awakening after surgery compared to those who did not receive it. Overall, tcVNS appears to be a safe and effective method to improve surgical recovery.¹²³⁶⁷