16 Participants NeededMy employer runs this trial

Creatine Gummies for Creatine Supplementation

SR
Overseen BySam R. Moore, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to compare how well creatine gummies raise creatine levels in the blood against the usual creatine powder. Since creatine enhances physical performance, the study tests these two forms to determine which is more effective. Participants are divided into two groups: one takes gummies first, then powder, and the other does the reverse. Recreationally active and healthy individuals without major diseases who meet certain lifestyle guidelines are suitable for this trial. As an unphased trial, it offers participants the opportunity to explore new methods for enhancing physical performance.

Will I have to stop taking my current medications?

If you are taking diuretics or corticosteroids, you will need to stop, as these medications can affect the study's results. If you're not on these medications, the protocol doesn't specify any other restrictions.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that creatine supplements are usually safe and don't cause major side effects. Many people take Create Wellness creatine gummies without problems, despite some debate about their actual creatine content. Evidence suggests that taking creatine in recommended amounts is likely safe for most people.

Creatine monohydrate powder is also recognized for its safety. Studies have found that even high doses of this form are safe for healthy individuals, even with long-term use. It has been used safely in amounts up to 30 grams per day for several years.

In summary, both creatine gummies and powder are generally safe when used as directed. No major safety concerns have been reported for either form in healthy adults.12345

Why are researchers excited about this trial?

Researchers are excited about Create Wellness Creatine Gummies because they offer a unique delivery method for creatine supplementation. Unlike traditional creatine monohydrate powders that require mixing with liquids, these gummies provide a convenient and tasty way to consume creatine, making it easier for individuals to incorporate into their daily routine. This innovative approach could improve adherence to supplementation, potentially enhancing performance outcomes for those seeking muscle strength and endurance benefits.

What evidence suggests that this trial's treatments could be effective for creatine supplementation?

Research has shown that creatine monohydrate powder, one of the treatments in this trial, can increase muscle strength, boost performance, and improve brain function. Studies have found that it aids in producing quick energy, which benefits short, intense activities. Creatine monohydrate is also considered safe and lacks major side effects.

Participants in this trial will also receive Create Wellness creatine gummies, which have mixed reviews. Some users report feeling more energetic and performing better, but tests have shown that many gummy brands contain little or no creatine. While research strongly supports the powder's effectiveness, the gummies' effectiveness can vary significantly depending on the brand and formulation.24678

Who Is on the Research Team?

SR

Sam R Moore, PhD

Principal Investigator

University of Oklahoma

Are You a Good Fit for This Trial?

This trial is for healthy adults. People with health conditions or on medications that could affect creatine metabolism, or those who are pregnant or breastfeeding, likely cannot participate.

Inclusion Criteria

Body mass index of less than 35 kg/m2
Recreationally active (≥30 minutes of moderate-intensity physical activity per week as defined by the International Physical Activity Questionnaire (IPAQ))
Agrees to complete pre-assessment guidelines (8-hour fast from caloric foods and beverages, 24-hour abstention from vigorous physical activity, caffeine, alcohol, and tobacco)
See 2 more

Exclusion Criteria

I have chronic kidney disease, liver disease, COPD, or cancer.
I am currently taking diuretics or corticosteroids.
I am currently taking creatine monohydrate.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
Phone screening and electronic consent

Baseline

Participants provide informed consent and complete a health/medical history questionnaire

1 day
Electronic consent and questionnaire submission

Treatment

Participants receive either Create Wellness creatine gummies or creatine monohydrate powder and undergo blood sampling

1 day per visit
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Create Wellness Creatine Gummies
  • Creatine Monohydrate Powder

Trial Overview

The study compares how quickly and effectively blood creatine levels rise after taking Create Wellness creatine gummies versus traditional creatine monohydrate powder in a single dose.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Sequence B (Powder, Gummy)Experimental Treatment2 Interventions
Group II: Sequence A (Gummy, Powder)Experimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Oklahoma

Lead Sponsor

Trials
484
Recruited
95,900+

Citations

Acute Pharmacokinetics of Create Wellness Gummies in ...

The purpose of this study is to compare blood creatine levels following acute oral supplementation of Create Wellness creatine gummies to ...

Those Creatine Gummies You Bought Online Might Not ...

Four of six popular creatine gummy products sold on Amazon contained almost no creatine or none at all when samples were tested by an independent lab.

Effects of Creatine Monohydrate Gummies on Performance ...

Conclusions: CrM supplementation delivered in gummy form enhanced selected performance outcomes and helped maintain body composition in female beach volleyball ...

NOW tests creatine gummies, identifies limitations in third ...

The experience of taking a creatine gummy that contains 1404 mg is virtually the same as taking a creatine gummy that contains 1500 mg of ...

Beware of most creatine gummies. Recent third-party testing ...

Beware of most creatine gummies. Recent third-party testing found that 2/3 of creatine gummy brands contained virtually no creatine, ...

Class action filed against Create Wellness for creatine ...

A lawsuit against Create Wellness alleges the company is falsely advertising that its gummies contain more creatine than they do.

Safety of creatine supplementation: analysis of the prevalence ...

Individual studies have indicated that creatine supplementation is generally well tolerated and not associated with clinically significant side effects.