Music Therapy for Childhood Cancer

RB
Overseen ByRobert Bennett, PhD, RN
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how learning to play the ukulele might enhance brain function in teens undergoing radiation treatment for cancer. Radiation can sometimes cause cognitive challenges, and music therapy could provide a fun and effective solution. The trial includes weekly virtual ukulele lessons and encourages independent practice. This music therapy is part of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention. Eligible teens have not previously taken ukulele or guitar lessons and are receiving their first round of radiation treatment at Mayo Clinic Arizona. Participants need access to a device capable of handling video calls. As an unphased trial, this study offers a unique opportunity to explore innovative ways to support cognitive health during cancer treatment.

What prior data suggests that the STRUM intervention is safe for adolescents undergoing radiation therapy?

Research has shown that music therapy is generally safe and well-tolerated for children and teens undergoing cancer treatment. Studies have found that it can reduce pain, enhance comfort, and lower stress levels. No major reports of harmful side effects from music therapy sessions exist. Importantly, music therapy has been linked to better quality of life, improved coping skills, and increased resilience. These findings suggest that participating in this therapy is not only safe but also beneficial for mental and emotional well-being.12345

Why are researchers excited about this trial?

Researchers are excited about the STRUM intervention because it's a fresh, non-medical approach to supporting kids with cancer by using music to boost mental resilience. Unlike traditional treatments that focus primarily on physical symptoms, STRUM offers virtual ukulele lessons that are designed to be fun and engaging, potentially helping to reduce stress and improve mood. This method is unique because it encourages creativity and self-expression, which can be empowering for young patients amidst their challenging treatment journeys.

What evidence suggests that the STRUM intervention is effective for improving cognitive decline in adolescents undergoing radiation therapy for cancer?

Research has shown that music therapy can benefit children and teens with cancer. Studies have found it improves their ability to handle challenges, interact with others, and relate to their families. Music therapy also reduces stress and anxiety, common during cancer treatment. Additionally, music activities enhance memory and emotional health, potentially counteracting the mental decline sometimes caused by radiation therapy. This trial will evaluate the STRUM program, which includes ukulele lessons, to determine if it offers similar benefits for teens undergoing cancer treatment.23678

Who Is on the Research Team?

CR

C. Robert Bennett, PhD, RN

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for teenagers with cancer who are receiving radiation therapy. It aims to help those at risk of memory or thinking problems caused by their treatment. Participants should be able to take part in virtual music lessons.

Inclusion Criteria

I am between 12 and 17 years old.
I am starting radiation therapy to cure my cancer at Mayo Clinic Arizona.
Able to provide assent
See 2 more

Exclusion Criteria

Less than three-month prognosis
I do not have vision, hearing, or thinking problems that prevent me from doing the study tasks.
I have received radiation therapy in the past.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Radiation

Participants undergo radiation therapy for cancer treatment

Varies based on individual treatment plans

STRUM Intervention

Participants receive virtual ukulele lessons to improve cognitive resilience

10 weeks
10 virtual sessions

Follow-up

Participants are monitored for safety and effectiveness after the intervention

8 weeks
Exit interview approximately 2 weeks after intervention

What Are the Treatments Tested in This Trial?

Interventions

  • Strengthening Teen Brain Resilience Using Music (STRUM) intervention

Trial Overview

The study tests if online ukulele music therapy sessions (STRUM intervention) can help teens keep their brains healthy during and after radiation treatment, compared to usual care. Interviews and surveys will also be used.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Supportive care (STRUM sessions)Experimental Treatment3 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Citations

The Role of Music Therapy for Children Undergoing Cancer ...

The aim of this study was to explore the benefits of music therapy (MT) for children with cancer over the course of their treatment in an ...

Effectiveness of music-based therapy on adolescents and ...

Music-based therapy has been shown to have numerous physical health benefits for adolescents and children with medical conditions (Wang & Xiao, 2021). · Music- ...

Music therapy has positive effects on young cancer ...

Music therapy has positive effects on young cancer patients' coping skills, social integration, and family environment

Music therapy improving health outcomes in children with ...

Music is becoming a powerful tool in pediatric care, easing stress and anxiety for children facing complex conditions like cancer. At the ...

Effectiveness of technology‐based psychosocial ...

technology-based psychosocial interventions created a favourable improvement in resilience in children and adolescents with cancer.

Impact of Music Therapy on Quality of Life in Children with ...

Conclusions: MT has positive impact on quality of life in children with cancer and reduces stress by lowering their cardiorespiratory rates.

Parental Perspectives on a Behavioral Health Music ...

Parental perspectives on music therapy interventions for children/adolescents with cancer offer a perspective on the benefit of such interventions, while ...

CACA guidelines for music-based interventions in oncology

The findings demonstrated that music therapy effectively alleviated pain, enhanced physical comfort, reduced fatigue while increasing energy, ...