Treadmill Training and Whole-body Vibration for Cerebral Palsy
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines whether combining whole-body vibration (WBV) with treadmill training (TT) can improve walking and reduce muscle tightness in children with cerebral palsy (CP). WBV alone provides short-term benefits, so researchers aim to determine if adding TT extends these benefits. Children with spastic CP who can walk and have not experienced recent injuries or Botox treatments are suitable candidates for this trial. As an unphased trial, it offers participants a unique opportunity to contribute to innovative research that could enhance treatment options for cerebral palsy.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have had Botox injections to the lower extremities in the past 3 months, you would not be eligible to participate.
What prior data suggests that whole-body vibration and treadmill training are safe for children with cerebral palsy?
Research shows that treadmill training is safe and effective for children with cerebral palsy (CP). Studies have found it helps improve walking distance and speed, which enhances movement. These studies report no major side effects from treadmill use, indicating it is well-tolerated.
Whole-body vibration (WBV) therapy has also been researched for children with CP. It has been shown to improve balance and reduce muscle stiffness. While WBV is generally considered safe, providers should remain aware of potential risks for children with disabilities. Overall, both treatments have proven effective and are usually well-tolerated in children with cerebral palsy.12345Why are researchers excited about this trial?
Researchers are excited about the use of treadmill training and whole-body vibration for cerebral palsy because these techniques offer a new approach to enhancing mobility and muscle function. Unlike traditional therapies that often focus on physical exercises and muscle strengthening, treadmill training provides a controlled environment for repetitive walking practice, potentially improving gait and endurance. Whole-body vibration, on the other hand, may stimulate muscle activity and improve muscle tone, offering a complementary benefit to the treadmill training. This combination could lead to more efficient and effective improvements in motor skills for individuals with cerebral palsy.
What evidence suggests that this trial's treatments could be effective for cerebral palsy?
Research has shown that treadmill training, a treatment in this trial, can help children with cerebral palsy improve walking and movement skills. One study found that treadmill training boosts recovery and physical responses in children with movement disorders. Similarly, whole-body vibration (WBV), another treatment option in this trial, shows promise in reducing muscle tightness and improving balance and strength in these children. Studies indicate that WBV can enhance lower limb function and prove more effective than other physical therapies. This trial will explore the potential benefits of combining these treatments to improve movement patterns and reduce muscle stiffness.12678
Who Is on the Research Team?
Jianhua Wu, PhD
Principal Investigator
Georgia State University
Are You a Good Fit for This Trial?
This trial is for children aged 6-17 with spastic Cerebral Palsy who can follow instructions on a treadmill. They should be able to walk (GMFCS level I, II, or III). Kids with recent musculoskeletal injuries, Botox treatments in the legs, significant heart issues, or uncontrolled seizures cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a 10-minute bout of treadmill training, rest for 15 minutes, followed by a 12-minute bout of whole-body vibration, and a second 10-minute bout of treadmill training
Follow-up
Participants are monitored for changes in gait parameters and spasticity immediately after the intervention
What Are the Treatments Tested in This Trial?
Interventions
- Treadmill Training
- Whole Body Vibration
Trial Overview
The study tests if adding Whole-body Vibration (WBV) to Treadmill Training (TT) helps improve walking and reduce muscle stiffness better than TT alone in kids with Cerebral Palsy. It looks at how one session of WBV might boost the benefits of a TT session.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
There are two intervention groups: treadmill walking only, whole-body vibration plus treadmill walking.
Treadmill Training is already approved in China for the following indications:
- Acute moderate ischemic stroke
Find a Clinic Near You
Who Is Running the Clinical Trial?
Georgia State University
Lead Sponsor
Citations
Feasibility, Safety, and Tolerability of Remote Ischemic ... - PMC
Remote ischemic conditioning (RIC) was feasible in children with unilateral cerebral palsy (CP), with excellent recruitment, retention, and full ...
effects of ischemic conditioning along with bimanual task ...
These results show that ischemic conditioning combined with bimanual task training greatly improves motor function and task efficiency in children with UCP.
Remote Limb Ischemic Conditioning to Enhance Muscle ...
conditioning (RLIC) can enhance quadriceps muscle power, dynamic balance and walking performance in children with cerebral palsy (CP).
Comparative analysis of the beneficial effects of treadmill ...
These results suggest that treadmill training and EA stimulation contribute to the enhancement of behavioral recovery following hypoxia-ischemia ...
Remote ischaemic conditioning combined with bimanual task ...
Studies comparing the efficacy of constraint-induced movement therapy and bimanual training in children with unilateral cerebral palsy: a systematic review.
Feasibility, Safety, and Tolerability of Remote Ischemic ...
Repeated RIC is feasible, safe, and tolerable in children with unilateral CP. These findings support the design of future trials using RIC ...
Remote Ischaemic Conditioning Combined With Bimanual ...
Expected outcomes. We predict that as compared with sham condition- ing+training, RIC+training will significantly: (1) increase cortical ...
Remote Ischemic Conditioning for Cerebral Palsy
Research has shown that Remote Ischemic Conditioning (RIC) is safe and well-tolerated in children with unilateral cerebral palsy, a movement ...
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