260 Participants Needed

Text Message Education for Heart Disease in HIV/AIDS

Recruiting at 1 trial location
MM
Overseen ByMegan McLaughlin, MD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, San Francisco
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether educational text messages (Digital Educational Messaging) can help people with HIV reduce their risk of heart disease. Participants in the experimental group will receive messages on their phones 3-5 times a week for up to six months, offering tips on heart health and information about HIV. Individuals who are HIV positive, over 40, and own a smartphone might be suitable for this trial. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance heart health for people living with HIV.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that Digital Educational Messaging is safe for persons living with HIV?

Research has shown that receiving educational text messages, like those used in this study, is generally safe. These messages aim to educate about the link between HIV and heart disease and how to reduce heart disease risk. No reports of harm have resulted from receiving these educational texts. Since this study involves only receiving information through texts, there are no physical risks. It focuses on helping people learn more about their health in a safe and simple way.12345

Why are researchers excited about this trial?

Researchers are excited about using digital educational messaging for heart disease prevention in people with HIV/AIDS because it offers a unique, non-invasive approach to managing risk. Unlike traditional treatments that might involve medications or lifestyle changes guided by healthcare providers, this method delivers important health information directly to patients through text messages. This can empower individuals by providing them with knowledge about HIV and heart disease risk, as well as practical tips to reduce that risk, all in a convenient and accessible format. The hope is that by reaching patients where they are—on their mobile devices—this approach can increase awareness and encourage proactive health management in an easy and engaging way.

What evidence suggests that digital educational messaging is effective for reducing cardiovascular risk in persons living with HIV?

Research has shown that text messaging can greatly improve heart health for people with HIV. Studies have found that text messages help people take their medications on time and lower their blood pressure, both crucial for reducing heart disease risk. Text messages have also successfully encouraged people to quit smoking, eat better, and exercise more. These lifestyle changes can significantly reduce heart disease risk. In this trial, participants in the intervention arm will receive regular, educational text messages about HIV and heart disease risk, potentially offering an easy and effective way to manage their heart health.12467

Who Is on the Research Team?

MM

Megan McLaughlin, MD, MPH

Principal Investigator

University of California, San Francisco

Are You a Good Fit for This Trial?

This trial is for English-speaking adults over 40 years old who are living with HIV but do not have existing cardiovascular disease. Participants must own a smartphone and be willing to provide informed consent. Pregnant individuals cannot participate.

Inclusion Criteria

I am 40 years old or older.
You have HIV.
English-speaking

Exclusion Criteria

I have heart disease related to artery blockage.
Pregnant
Unwilling/unable to provide informed consent
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive educational text messages about HIV and heart disease risk 3-5 times per week for up to 6 months

6 months
Monthly surveys via digital platform

Follow-up

Participants are monitored for cardiovascular risk factors and health outcomes after the intervention

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Digital Educational Messaging
Trial Overview The TEACH-HIV trial is testing whether educational text messages can help reduce the risk of heart disease in people with HIV. The effectiveness of these digital messages will be evaluated over time.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Intervention ArmExperimental Treatment1 Intervention
Group II: Control ArmActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials
2,636
Recruited
19,080,000+

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Trials
3,987
Recruited
47,860,000+

Published Research Related to This Trial

Text messaging interventions have been shown to effectively improve adherence to antiretroviral therapy and increase appointment attendance among people living with HIV, based on a systematic review of nine high-quality reviews involving 37 studies across 19 countries.
There are significant knowledge gaps regarding long-term outcomes and patient satisfaction with text messaging interventions, indicating a need for further research to fully understand their impact and potential in managing other chronic diseases.
Mobile phone text messaging interventions for HIV and other chronic diseases: an overview of systematic reviews and framework for evidence transfer.Mbuagbaw, L., Mursleen, S., Lytvyn, L., et al.[2022]
A review of 51 studies highlighted the importance of developing SMS content for mHealth initiatives aimed at supporting HIV/AIDS treatment adherence, emphasizing the need for formative research and grounding messages in behavior change theory.
Best practices for creating effective SMS messages include consulting with experts and using established behavior change frameworks to enhance the effectiveness of mobile health interventions in resource-limited settings.
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: a review of the literature.Kerrigan, A., Kaonga, NN., Tang, AM., et al.[2023]
A cluster randomized trial involving 13,937 pregnant women in Hunan, China, tested a maternal education program delivered via text messaging, but the results showed no statistically significant differences in maternal and perinatal mortality rates between the intervention and control groups.
While the intervention arm had slightly lower rates of maternal (0.04% vs. 0.09%) and perinatal deaths (1.24% vs. 1.45%), the study suggests that larger trials with more intensive implementation are needed to confirm any potential benefits of SMS-based maternal education.
The Impact of a Maternal Education Program Through Text Messaging in Rural China: Cluster Randomized Controlled Trial.Xie, RH., Tan, H., Taljaard, M., et al.[2020]

Citations

Development of text messages for primary prevention ...We sought to develop a bank of text messages about (1) the association between HIV and CVD and (2) advice on reducing cardiovascular risk.
Development of text messages for primary prevention ...We sought to develop a bank of text messages about (1) the association between HIV and CVD and (2) advice on reducing cardiovascular risk. Methods We developed ...
Text messages as a tool to improve cardiovascular disease ...Text messaging interventions effectively improve medication adherence and reduce blood pressure, making them a promising tool for CVD risk control.
Development of text messages for primary prevention ...We sought to develop a bank of text messages about (1) the association between HIV and CVD and (2) advice on reducing cardiovascular risk.
Effect of Text Messaging on Risk Factor Management in ...Text messaging is shown to be effective in risk factor modifications, such as smoking cessation, healthy dietary habits, increased physical activity, and ...
Study Details | NCT05711004 | Efficacy of Education Via ...Study Overview. Brief Summary. Uncontrolled hypertension (HTN) is a major public health worldwide, which increases the risk of cardiovascular diseases.
7.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/38222100/
Development of text messages for primary prevention ...We describe an approach for developing educational text messages on primary prevention of cardiovascular disease among PWH.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security