Cognitive-Behavioral Therapy for Binge Eating
(CARE2 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests two treatments for adolescents who frequently binge eat and are above the 85th percentile for their age and sex in weight. The treatments compared are cognitive-behavioral therapy (CBT), a type of talk therapy, and a lifestyle program focusing on healthy habits. A control group tracks their eating and mood using an app. The aim is to determine which method best reduces binge eating and aids in weight management. Teens who have experienced at least four binge-eating episodes per month over the last three months may be suitable for this study. As an unphased trial, this study offers a unique opportunity to contribute to understanding effective treatments for binge eating in adolescents.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Studies have shown that cognitive-behavioral therapy (CBT) is safe and effective for treating binge eating in teenagers. Research indicates that CBT reduces binge-eating episodes and is generally well-tolerated, with no major side effects reported. This makes it a reliable option for many teens facing this issue.
For the lifestyle behavioral obesity intervention (LBOI), research suggests it is also safe and helps teenagers manage their weight and improve eating habits. A recent review found that these programs do not increase the risk of eating disorders and may even reduce binge-eating symptoms. This intervention is considered a first-choice treatment for teenagers dealing with obesity and related challenges.
Both CBT and LBOI provide supportive and structured ways to address binge eating and obesity, with a strong safety record.12345Why are researchers excited about this trial?
Researchers are excited about these treatments for adolescent binge eating because they offer innovative approaches that differ from traditional methods. Cognitive-Behavioral Therapy (CBT-BED) and Lifestyle Behavioral Obesity Intervention (LBOI) are both delivered remotely via telehealth, making them more accessible to teens who might struggle with in-person visits. While CBT-BED focuses on identifying and changing negative thought patterns associated with binge eating, LBOI emphasizes lifestyle changes to manage weight and eating habits. The use of telehealth also allows for greater flexibility and convenience, potentially increasing adherence and effectiveness compared to standard in-person therapy sessions.
What evidence suggests that this trial's treatments could be effective for binge eating?
Research has shown that cognitive-behavioral therapy (CBT), one of the treatments in this trial, can help reduce binge eating in teenagers. Studies have found that CBT leads to fewer binge eating episodes and better eating habits. For instance, one study reported that CBT resulted in a decrease in binge eating and improved overall eating behavior.
In contrast, the lifestyle behavioral obesity intervention (LBOI), another treatment option in this trial, effectively promotes weight loss. These programs focus on healthy eating and exercise and have demonstrated significant weight loss compared to no intervention. However, LBOI generally does not reduce binge eating as effectively as CBT.16789Are You a Good Fit for This Trial?
This trial is for adolescents who struggle with binge eating and are overweight or have obesity. Participants must be able to join remotely from most states in the U.S. The study is not for those without these eating or weight concerns.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either CBT-BED, LBOI, or engage in Active Control self-monitoring for 6 months
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive-Behavioral Therapy for Adolescent Binge Eating
- Lifestyle Behavioral Obesity Intervention
Trial Overview
The study compares two online treatments: cognitive-behavioral therapy (CBT) focused on binge eating, and a lifestyle program aimed at healthy habits and weight loss. There's also a control group using an app to track food intake and mood.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Active Control
Lifestyle behavioral obesity intervention (LBOI) for adolescents with binge eating and overweight or obesity, delivered remotely by telehealth.
Cognitive-behavioral therapy for binge-eating disorder (CBT-BED) for adolescents with binge eating and overweight or obesity, delivered remotely by telehealth.
Active control: daily self-monitoring of eating, emotions, and physical activity via an "app," similar to real-world digital self-help. At the end of the initial period, individuals are presented with descriptions of CBT-BED and LBOI, choose their preferred treatment, and receive it.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Indiana University
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Citations
1.
eatingdisorderhope.com
eatingdisorderhope.com/treatment-for-eating-disorders/eating-disorder-hotlinesEating Disorder Hotlines for Crisis Help
There are several eating disorder hotlines you can call if you or someone you know needs help with an eating disorder.
Effectiveness of a Web-Based Cognitive Behavioral Self ...
The web-based intervention led to significant improvements in binge eating episodes (Cohen d, −0.79 [95% CI, −1.17 to −0.42]; P < .001), ...
Cognitive behavioral therapy for eating disorders - PMC - NIH
High intensity CBT was more effective compared to mixed active controls in reducing ED behaviors and psychopathology (see Table 3). It was also ...
A systematic review of cognitive behavior therapy and ...
By the end of treatment, patients reported significant improvements in global eating disorder psychopathology, binge eating, and vomiting, and ...
NCT04088097 Cognitive Behavioral Therapy for ...
Cognitive-behavioral therapy (CBT) has a strong evidence base for adult BED (20-25). is unclear (30- 34). parental involvement improves weight outcomes (29, 36 ...
Cognitive-behavioral therapy for binge eating disorder in ...
BED has been identified in 1.6% of 13- to 18-year-old adolescents from the community [3], and in up to 25% of treatment-seeking adolescents
NCT04088097 Cognitive Behavioral Therapy for ...
A cognitive-behavioral adaptation for adolescents with recurrent binge eating (with or without purging) had a small sample and used a delayed-treatment control ...
Behavioral Therapy for Eating Disorders in Children & ...
CBT may help adolescents or younger children cope with issues that trigger binge-eating episodes, such as negative feelings about the body or a depressed mood.
Enhanced Cognitive Behavioral Therapy (CBT-E) for ...
Current guidelines inform that CBT-E is the most appropriate alternative to FBT for adolescents with anorexia nervosa or bulimia nervosa.
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