40 Participants NeededMy employer runs this trial

Tai Chi for Breast Cancer

KW
Overseen ByKuang-Yi Wen, PhD
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: Thomas Jefferson University
Must be taking: Aromatase inhibitors
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether Tai Chi can relieve joint pain caused by certain breast cancer treatments. It compares Tai Chi sessions to regular health education sessions to determine which is more effective. The trial targets women with postmenopausal breast cancer who experience joint pain after starting hormone therapy. Participants should not already engage in regular exercise or Tai Chi. As an unphased trial, this study provides a unique opportunity to explore alternative pain relief methods.

What prior data suggests that Tai Chi is safe for women with breast cancer?

Research has shown that Tai Chi is generally safe for breast cancer patients. Studies have found it can improve both physical and mental health after treatment. For example, Tai Chi helps with tiredness and stress. As a gentle exercise, it is easy on the body and usually doesn't cause injuries.

Patients also respond well to Tai Chi. In various studies, participants continued with the exercise routines as well as or better than other activities like Qigong or dancing. This suggests they find it easy and safe to do regularly.

Overall, the evidence supports Tai Chi as a safe choice for enhancing recovery and quality of life after breast cancer treatment.12345

Why are researchers excited about this trial?

Unlike conventional treatments for breast cancer, which often involve surgery, chemotherapy, or radiation therapy, Tai Chi offers a holistic approach through gentle, structured movements. Researchers are excited about this treatment because it emphasizes mindfulness, postural alignment, and integrated movement, which can potentially enhance physical and emotional well-being without the side effects of more invasive treatments. This method not only aims to improve physical strength and endurance but also promotes relaxation and mental focus, providing a comprehensive way to support recovery and quality of life for breast cancer survivors.

What evidence suggests that Tai Chi might be an effective treatment for breast cancer?

Research has shown that Tai Chi can benefit people with breast cancer. Studies have found that it improves quality of life and reduces symptoms such as anxiety, depression, and fatigue. Tai Chi also eases pain associated with breast cancer. Some research suggests it might lower inflammation in breast cancer survivors. In this trial, participants will be randomized into either the TaiChi4Joint group, attending virtual Tai Chi classes, or the Health Education Attention Control group, participating in routine virtual classes on survivorship content or healthy eating. While results can vary, these findings suggest Tai Chi could be a valuable addition to breast cancer treatment.14567

Who Is on the Research Team?

KW

Kuang-Yi Wen, PhD

Principal Investigator

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Are You a Good Fit for This Trial?

This trial is for postmenopausal women with stage I-III hormone receptor-positive breast cancer who are experiencing joint pain from taking aromatase inhibitors.

Inclusion Criteria

Postmenopausal
I have joint pain that began or got worse after starting AI therapy.
Able to complete study procedures in English
See 5 more

Exclusion Criteria

I am currently receiving active cancer treatment, not including hormone therapy.
Currently engaged in regular structured moderate- or vigorous-intensity exercise totaling ≥150 minutes per week over the past 3 months
I have had surgery or a joint injection in the last 4-6 weeks.
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are randomized to either the TaiChi4Joint group or a health education AC group for 12 weeks, attending virtual classes twice a week

12 weeks
24 virtual sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment with assessments at post-intervention and 2-month post-intervention follow-up

8 weeks
2 follow-up assessments

What Are the Treatments Tested in This Trial?

Interventions

  • Tai Chi

Trial Overview

The study compares Tai Chi exercises to health education classes to see which helps more with joint pain caused by breast cancer medication. Participants are randomly assigned to one of the two groups.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: TaiChi4JointExperimental Treatment1 Intervention
Group II: Health Education Attention ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Thomas Jefferson University

Lead Sponsor

Trials
475
Recruited
189,000+

Citations

Effect of Tai Chi Chuan in Breast Cancer Patients - PMC - NIH

Conclusions: TCC appears to be effective on some physical and psychological symptoms and improves the quality of life in patients with breast cancer. Additional ...

The effectiveness of tai chi in breast cancer patients

Tai chi significantly improves overall quality of life at 3 months compared to conventional therapy. • Tai chi+conventional therapy is more effective in ...

The effects of Tai Chi and Baduanjin on breast cancer ...

Chi and Baduanjin significantly reduced anxiety symptoms, depression symptoms, and fatigue symptoms among breast cancer patients.

Best Mind-Body Therapies for Cancer Pain? Qigong and ...

When it comes to relief from breast cancer pain, recent research suggests tai chi comes out on top. The findings appeared in the journal ...

The Effectiveness of Tai Chi in Patients With Breast Cancer

Among these outcome indicators, the quality of evidence was high in 1, moderate in 2, low in 5, and critically low in 12.

Tai Chi

Tai chi is a low-impact exercise and is considered to be relatively safe. However, as with any practice, there are precautions you should take ...

What the Evidence Says About Tai Chi in Cancer Care

In another study that evaluated the effects of tai chi on symptom clusters in breast cancer, 69 patients were randomized to eight weeks of usual ...