3D Ultrasound for Breast Disease

This trial tests a new 3D ultrasound method for identifying tumors and other key features in the breast. Participants will have additional 3D images taken during their regular mammogram and ultrasound appointments. The goal is to determine if the 3D images offer a clearer view than the standard 2D ultrasound. Females scheduled for routine breast screening or short-term follow-up with ultrasound may qualify, provided they do not have breast implants. As an unphased trial, this study allows participants to contribute to innovative imaging techniques that could improve breast cancer detection.

The trial information does not specify whether you need to stop taking your current medications.

Research has shown that 3D ultrasound for breast imaging is generally well-received by patients. Studies indicate that automated 3D ultrasound can help detect breast cancer, especially in women with dense breast tissue. This method supports existing screening techniques, ensuring safety. Its accuracy is similar to that of regular mammograms, which is a positive indicator for safety. Although this study uses a new device for 3D imaging, the overall technique has been safely used in other contexts. Therefore, prospective trial participants can feel confident about the procedure's safety.¹²³⁴⁵

Researchers are excited about 3D ultrasound for breast disease because it offers a new way to visualize breast tissue in three dimensions, unlike traditional 2D mammograms and ultrasounds. This advanced imaging technique could provide more detailed and accurate insights into breast abnormalities, potentially leading to earlier and more precise detection of breast cancer. By capturing comprehensive 3D volumes, it aims to reduce false positives and negatives, which are common challenges with current screening methods. This could significantly improve patient outcomes by ensuring timely and accurate diagnosis.

Research shows that 3D ultrasound imaging effectively detects breast cancer that a regular mammogram might miss, especially in women with dense breast tissue. Studies have found that 3D automated breast ultrasound (3D ABUS) can detect more cancer cases, with a detection rate of 1.9 to 7.7 per 1000 women screened. This method provides a clearer view of breast tissue, making tumors easier to spot compared to traditional 2D imaging. These findings suggest that 3D ultrasound could be a valuable tool for early cancer detection, offering more detailed images than standard methods. Participants in this trial will be imaged with an experimental device designed to acquire ultrasound in three-dimensional volumes.¹⁶⁷⁸⁹