200 Participants NeededMy employer runs this trial

Portable MRI for Pediatric Brain Injury

(pMRI for HIBI Trial)

Recruiting at 1 trial location
JS
AS
HM
Overseen ByHannah Mendenhall, BSN, RN, CPN
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Children's Mercy Hospital Kansas City
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will evaluate the sensitivity and specificity of low field portable MRI (pMRI) for detection of hypoxic ischemic brain injuries in pediatric patients compared to clinically obtained neuroimaging to define pediatric diagnostic limitations and to determine the diagnostic capabilities of this neuroimaging modality following optimization of image acquisition. The results of this study will help determine optimal clinical implementation opportunities in pediatric patients.

Who Is on the Research Team?

JS

Jessica S Wallisch, MD

Principal Investigator

Children's Mercy Kansas City

Are You a Good Fit for This Trial?

This trial is for children and teens (newborn to 17 years old) in intensive care units who have or are at high risk for brain injury due to lack of oxygen. Participants must be hospitalized with a suspected recent brain problem caused by low oxygen.

Inclusion Criteria

Patients hospitalized in the Pediatric Intensive Care Unit, Cardiac Intensive Care Unit, or the Neonatal Intensive Care Unit
I am between 0 and 17 years old.
I have or am at high risk for brain injury due to lack of oxygen.

Exclusion Criteria

Former or current welders, metal workers, or individuals with a metal injury
MRI incompatible surgical hardware (e.g., staples, screws, etc.)
Pregnancy
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Perform portable MRI (pMRI) on pediatric ICU patients to evaluate sensitivity and specificity for detecting brain injuries

1 month
Multiple visits during ICU admittance

Follow-up

Participants are monitored for safety and effectiveness after pMRI procedures

4 weeks

What Are the Treatments Tested in This Trial?

Trial Overview

The study is testing how well a portable MRI scanner can detect brain injuries from low oxygen in kids, compared to standard hospital imaging. It also collects leftover samples like blood or fluids for analysis.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Portable MRI ArmExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Children's Mercy Hospital Kansas City

Lead Sponsor

Trials
261
Recruited
941,000+