Multisensory Rehabilitation for Hemianopia

KH
WJ
Overseen ByWendy Jenkins, BSNRN, CCRC
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Wake Forest University Health Sciences
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new treatment called multisensory rehabilitation to assist individuals with hemianopia, a condition causing blindness on one side of the visual field due to brain damage. The goal is to determine if this method can enhance vision and alleviate the suffering associated with this condition. Participants will undergo a series of visual tests and training sessions to monitor any improvements. Individuals with stable hemianopia for more than four weeks, without additional issues like hemineglect (difficulty noticing things on one side), may be suitable candidates for this trial. As an unphased trial, this study provides a unique opportunity to contribute to groundbreaking research that could lead to new treatment options.

What prior data suggests that this multisensory rehabilitation is safe for hemianopia patients?

Research has shown that multisensory rehabilitation is safe for people with hemianopia, a condition characterized by the loss of half of the visual field. This method employs various senses to enhance vision. Studies indicate that this training is well-tolerated and typically does not cause serious side effects. Participants in previous research completed multisensory exercises without major issues, suggesting that the treatment is generally safe to try.12345

Why are researchers excited about this trial?

Researchers are excited about multisensory rehabilitation for hemianopia because it takes a unique approach by combining multiple sensory inputs to enhance visual recovery. Unlike standard treatments that primarily focus on compensatory strategies like visual scanning or prism glasses, this method aims to directly stimulate visual field recovery. Additionally, the treatment's tailored follow-up sessions provide ongoing support to maintain and potentially improve any initial visual gains, setting it apart from traditional approaches that often lack such personalized and dynamic intervention.

What evidence suggests that multisensory rehabilitation is effective for hemianopia?

Research has shown that multisensory rehabilitation, the treatment under study in this trial, can help people with hemianopia regain some vision. Hemianopia occurs when someone loses half of their field of vision due to brain damage. One study found that this therapy works quickly and effectively to improve vision. Another study demonstrated that even remote therapy, through telerehabilitation, helps patients adjust to their vision loss. Additionally, a short session using both sound and visual stimulation improved vision. These findings suggest that multisensory rehabilitation could enhance life for those with hemianopia.12367

Who Is on the Research Team?

BR

Benjamin Rowland, PhD

Principal Investigator

Wake Forest University Health Sciences

Are You a Good Fit for This Trial?

This trial is for people who have lost part of their vision due to damage in the visual cortex of the brain, such as those with hemianopia or cortical blindness. Participants must have this type of vision loss and meet other basic health requirements.

Inclusion Criteria

Patients will be recruited from the local subject population hospitalized/seen by Ophthalmology, Neurosurgery, and Neurology at Atrium Health Wake Forest Baptist
I am willing to take part in a three-month program.
Ability to perform visual discriminations in their intact field
See 4 more

Exclusion Criteria

Any other condition that would compromise their ability to complete the study
Inability to perform the visual testing in their intact field
I have unstable vision loss or neglect on one side of my visual field.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Initial Treatment

Participants engage in a multisensory training paradigm over 12 research sessions with clinical visits at the first and last session

12 sessions
12 research sessions + clinical visits at the first and last session

Follow-up

Participants undergo follow-up procedures to assess visual recovery, with additional visits if vision has degraded

3 months
1 research visit, 2-5 additional visits if needed

Long-term Follow-up

Participants are monitored for changes in NIHSS and Activity Inventory scores

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Multisensory Rehabilitation

Trial Overview

The study is testing a multisensory rehabilitation program designed to help improve vision after brain-related vision loss. The goal is to see if combining different senses can aid recovery.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: multisensory trainingExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials
1,432
Recruited
2,506,000+

Citations

Ameliorating Hemianopia with Multisensory Training

These results indicate that the multisensory therapy is a rapid and effective method for restoring visual function in hemianopia.

An Audiovisual 3D-Immersive Stimulation Program in ...

Here, we obtained promising results demonstrating that a total of 3 h 20 min of audiovisual IVR stimulation procedure is sufficient to improve visual function ...

Telerehabilitation for visual field defects with a multisensory ...

Multisensory training delivered in telerehabilitation is feasible and effective for ameliorating oculomotor compensation of visual field loss, ...

Case Report: Visual Rehabilitation in Hemianopia Patients ...

Standard visual outcomes assessed in usual care in visual rehabilitation were measured at the clinic. Following a mixed method approach in this ...

Multisensory Rehabilitation for Hemianopia

Research has shown that multisensory rehabilitation is safe for people with hemianopia, a condition where half of the field of vision is lost. Past studies ...

Multisensory Rehabilitation of Hemianopia - ClinicalTrials.Veeva

The over-arching objective is to evaluate the functional recovery of vision in hemianopic patients engaged with a multisensory training paradigm ...

Ameliorating Hemianopia with Multisensory Training - PMC

These results indicate that the multisensory therapy is a rapid and effective method for restoring visual function in hemianopia.