Senyo Health App for Substance Abuse in Bipolar Disorder

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Overseen ByBryce Leatherman
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new app called Senyo Health, designed to help individuals with bipolar disorder manage substance use, such as alcohol consumption. The main goal is to determine if the app can improve adherence to treatment and reduce the frequency and quantity of substance use. This study suits individuals with bipolar disorder who also struggle with alcohol use and have access to a smartphone for daily app use.

As an unphased trial, it offers participants a unique opportunity to contribute to innovative research that could enhance treatment strategies for bipolar disorder and substance use.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the Senyo Health app is safe for use in patients with Bipolar Disorder?

Research has shown that digital tools like the Senyo Health app can safely assist in treating substance use disorder (SUD). Other studies have found that people generally find digital health tools easy to use. For instance, one study demonstrated that patients using a smartphone app for self-monitoring used it consistently. They also experienced improvements in symptoms related to bipolar disorder, with depressive symptoms decreasing by 41%, manic symptoms by 46%, and overall symptom instability by 39%.

These results suggest that digital health tools, including the Senyo Health app, could be a safe option for managing substance use issues. These studies reported no major negative side effects, indicating that the app is generally well-received.12345

Why are researchers excited about this trial?

Researchers are excited about the Senyo Health app because it offers a novel approach to managing substance abuse in individuals with bipolar disorder. Unlike traditional treatments, which often rely on medication and therapy, the Senyo Health app provides a digital, interactive platform that users engage with daily for 12 weeks. This app leverages technology to deliver personalized support and track progress in real-time, potentially increasing accessibility and engagement for patients who may struggle with regular in-person treatment sessions. The use of a digital tool is particularly promising as it could offer a more flexible and immediate form of assistance, helping to address the unique challenges faced by this population.

What evidence suggests that the Senyo Health app is effective for substance abuse in Bipolar Disorder?

Studies have shown that the Senyo Health app can help people reduce their substance use. It employs a digital platform to support patients and healthcare providers with SBIRT, which stands for Screening, Brief Intervention, and Referral to Treatment. Research indicates that users of this app often reduce their substance use more than those relying on traditional treatments. In this trial, participants will use the Senyo Health app daily for 12 weeks. The app aims to keep individuals engaged in their treatment, which is crucial for managing substance use in those with bipolar disorder. Early findings suggest that this type of digital support can improve outcomes for individuals dealing with both bipolar disorder and substance use issues.12456

Who Is on the Research Team?

MA

Mark A. Frye, MD

Principal Investigator

Mayo Clinic

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Tyler S. Oesterle, MD, MPH

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for adults who have bipolar I, bipolar II, or schizoaffective disorder (bipolar type) and also struggle with alcohol use disorder. Participants must be able to read English, use a smartphone or tablet for care sessions, and meet certain screening scores.

Inclusion Criteria

I have been diagnosed with bipolar disorder or schizoaffective bipolar type.
* Alcohol use disorder.
* Ability to read, write, and understand English;
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants utilize the Senyo Health app daily to improve substance use outcomes

12 weeks
Weekly virtual check-ins

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months
Monthly virtual assessments

What Are the Treatments Tested in This Trial?

Interventions

  • Senyo Health

Trial Overview

The study tests the Senyo Health App—a digital behavioral health platform—to see if it helps people with bipolar disorder and alcohol problems stay in treatment longer and reduce substance use.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Senyo Health appExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+

Citations

A Study Of Senyo Health With Comorbid Alcohol Use ...

The purpose of this study is to examine the effectiveness of a digital integrated behavioral health (IBH) platform in improving substance use ...

Treatment of Substance Use Disorders With a Mobile Phone ...

Senyo Health is a digital tool to facilitate the use of SBIRT in primary care. It contains a web-based platform for clinician and staff use and a patient-facing ...

Senyo Health App for Substance Abuse in Bipolar Disorder

The purpose of this study is to examine the effectiveness of a digital integrated behavioral health (IBH) platform in improving substance use outcomes, ...

Digital Therapeutic Content for Substance Use Disorder ...

Background: Substance use disorders (SUDs) are a major public health concern, contributing to significant individual and societal costs.

Treatment of Substance Use Disorders With a Mobile ...

This study aims to evaluate the implementation and clinical effectiveness of Senyo Health, a digitally native, addiction treatment and CoCM ...

6.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/40138685/

Protocol for a Mixed Methods Randomized Controlled Trial

This protocol describes a novel use of the SBIRT pathway using Senyo Health to complement existing CoCM integration within primary care to deliver SUD ...