Milieu Teaching-AV for Autism

(MilieuTeach-AV Trial)

JI
Overseen ByJacob I Feldman, PhD, CCC-SLP
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Father Flanagan's Boys' Home
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores new ways to help infants with older siblings with autism improve their communication and language skills. It compares two methods of Milieu Teaching, a language intervention: one uses audiovisual cues to encourage infants to look at caregivers' faces, and the other does not. The researchers aim to determine if the version with audiovisual cues helps babies engage more with caregivers and develop better language skills. Families with a baby aged 6-12 months, who has an older sibling with autism and speaks only English at home, might be a good fit for this trial. As an unphased trial, this study offers families the chance to contribute to innovative research that could enhance early language development strategies.

Will I have to stop taking my current medications?

The trial information does not specify whether participants need to stop taking their current medications.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that Milieu Teaching-AV is generally safe for children with autism. Studies have found that this language program does not cause any major negative effects and is designed to improve communication skills. Children in various studies demonstrated positive results, such as increased language use and improved social interactions. While no treatment is entirely without risk, evidence suggests that Milieu Teaching-AV is safe for children in these studies.12345

Why are researchers excited about this trial?

Researchers are excited about the Milieu Teaching-AV technique for autism because it introduces a novel interaction strategy that enhances communication between caregivers and infants. Unlike traditional therapies that may not emphasize the physical positioning of objects during communication, this method trains caregivers to strategically move items near the mouth, guiding the infant's gaze and attention. This approach could improve the infants' ability to focus and respond during interactions, potentially leading to more effective communication development. By refining how caregivers engage with infants, this technique could offer a fresh and promising direction in supporting early communication skills in children with autism.

What evidence suggests that this trial's treatments could be effective for autism?

Studies have shown that Milieu Teaching-AV, one of the methods tested in this trial, uses visual and audio cues to enhance communication skills in children with autism. This method encourages children to look at caregivers' faces, boosting their language skills and engagement. Research on similar methods has demonstrated improvements in learning new words and social interactions. For example, one study found that children using these strategies increased their communication behaviors. Overall, Milieu Teaching-AV is generally well-tolerated and effective for enhancing language skills in children with autism. Another method tested in this trial is Milieu Teaching-NoAV, which serves as an active comparator.12367

Are You a Good Fit for This Trial?

This trial is for infants aged 6-12 months who have an older sibling diagnosed with autism, live in English-speaking homes, and do not have neurological issues, genetic conditions, preterm birth (before 37 weeks), or diagnosed vision/hearing problems.

Inclusion Criteria

I have an older sibling diagnosed with autism.
I live in a household where only English is spoken.
My child is between 6 and 12 months old.

Exclusion Criteria

Adverse neurological history
I have a diagnosed genetic condition.
Pre-term birth (gestation < 37 weeks)
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive Milieu Teaching-AV or Milieu Teaching-NoAV intervention, with sessions anticipated as 1 hour, 2 times per week, for up to 3 months

12 weeks
24 visits (in-person)

Follow-up

Participants are monitored for language and engagement outcomes after the intervention

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Milieu Teaching-AV
  • Milieu Teaching-NoAV

Trial Overview

The study compares two language teaching methods: one that encourages babies to look at caregivers' faces while speaking (Milieu Teaching-AV) versus standard Milieu Teaching without this focus. The goal is to see which method better supports communication and engagement.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Milieu Teaching-AVExperimental Treatment1 Intervention
Group II: Milieu Teaching-NoAVActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Father Flanagan's Boys' Home

Lead Sponsor

Trials
14
Recruited
1,600+

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborator

Trials
377
Recruited
190,000+

Citations

Study Details | NCT06794476 | Milieu Teaching-AV (MT- ...

This project will look at whether a novel approach to language intervention that encourages looking to audiovisual speech cues for infants with autistic ...

Effectiveness of Responsivity Intervention Strategies on ... - PMC

This systematic review and meta-analysis provides empirical support for the use of responsivity intervention strategies to improve prelinguistic and language ...

Enhanced milieu teaching for children with autism spectrum ...

Conclusion. Results indicated that EMT may be effective for improving communication in South African children with ASD. Implications for ...

Milieu Teaching-AV for Autism

Studies have shown that Milieu Teaching-AV, a language intervention, is generally well-tolerated by children with autism. Research on similar methods, such as ...

Adaptation of Milieu Teaching That Encourages Looking to the ...

This strategy has already been shown to boost word learning in autistic preschoolers, at least for proximal targets (i.e., for words that were ...

(PDF) The Effects of Trainer-Implemented Enhanced Milieu ...

Observational data indicated that all children showed positive increases for specific target language use at the end of 24 intervention sessions, and these ...

Impact of milieu teaching on communication skills of young ...

Results indicated that milieu strategies are an effective means of providing communication skills instruction for young children with ASD in an ECSE classroom.