Bachmann's Bundle vs Right Atrial Appendage Pacing for Atrial Fibrillation
(BACH-RAP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Participants will be randomly assigned to one of two clinical treatment Arms, both of which are standard care procedures performed in the right atrium (RA):
Arm A: Pacing from the Bachmann's Bundle (BB) in the right atrium (upper right chamber of the heart) Arm B: Pacing from the right atrial appendage (RAA - a sac attached to the right atrium) Neither of these treatments are experimental; both are routinely performed by Electrophysiologists in the clinical setting. The purpose of this study is to compare side by side these two treatments and evaluate if one is better than the other. After the procedure, participants will be followed for one year.
Medical record data will be collected, and a blood sample will be collected upon enrollment and at one year after implantation. Research-related surveys will be completed at the standard-care 3-, 6-, and 12-month visits.
Who Is on the Research Team?
Joshua Silverstein, MD
Principal Investigator
Allegheny Health Network
Are You a Good Fit for This Trial?
This trial is for people with atrial fibrillation who need a pacemaker in the right atrium. Participants should be able to attend follow-up visits and provide blood samples. Specific inclusion or exclusion criteria are not detailed here.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Trial Overview
The study compares two standard ways of placing pacemaker leads: one at Bachmann's Bundle and the other at the right atrial appendage. Participants are randomly assigned to either group, and both procedures are commonly used by heart specialists.
How Is the Trial Designed?
2
Treatment groups
Active Control
Standard Clinical BB Pacing
Standard Clinical RAA Pacing
Find a Clinic Near You
Who Is Running the Clinical Trial?
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Lead Sponsor
Medtronic
Industry Sponsor
Geoff Martha
Medtronic
Chief Executive Officer since 2020
Finance degree from Penn State University
Dr. Richard Kuntz
Medtronic
Chief Medical Officer since 2023
MD, MSc
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.