CT Scan for Atrial Fibrillation
(ELATE-AF Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study aims to investigate whether a quick, additional CT scan of the heart, performed immediately after a standard CT scan for pulmonary embolism, can effectively detect blood clots in the left atrial appendage (LAA) in patients with atrial fibrillation. Detecting these clots is crucial before certain heart procedures to prevent stroke. Currently, a different, more involved procedure (Transesophageal Echocardiography - TEE) is often used. This study will assess if this additional CT scan is feasible, meaning if it can provide clear enough images to identify LAA clots without needing more contrast dye. The study will involve 60 patients, half receiving an "ungated" CT scan and the other half a "gated" CT scan (timed with their heart rhythm). The results of these scans will not be used for immediate patient care during the study, but rather to evaluate the CT scan technique itself. There is no direct benefit to participants, but the information gained could lead to faster diagnosis and reduced unnecessary testing for future patients.
Are You a Good Fit for This Trial?
This trial is for adults in the emergency department with atrial fibrillation who are already getting a CT scan to check for a lung blood clot. There are no detailed inclusion or exclusion criteria listed, but participants must be able to undergo an extra heart CT scan.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
CT Scan Procedure
Participants undergo a quick, additional CT scan of the heart immediately after a standard CT scan for pulmonary embolism
Data Analysis
The results of the CT scans are analyzed to evaluate the technique's feasibility and diagnostic accuracy
Follow-up
Participants are monitored for any adverse effects and the study outcomes are assessed
What Are the Treatments Tested in This Trial?
Trial Overview
The study compares two types of quick heart CT scans—one timed with the heartbeat (gated) and one not (ungated)—done right after a standard chest CT. The goal is to see if these scans can reliably spot clots in the left atrial appendage.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
This arm will include the first 30 patients, who will undergo a 60-second delayed, un-gated CT scan to assess the left atrial appendage.
This arm will include the subsequent 30 patients, who will undergo a 60-second delayed, gated CT scan to assess the left atrial appendage.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwell Health
Lead Sponsor
Canon Medical Systems, USA
Industry Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.