100 Participants NeededMy employer runs this trial

Constant Therapy Program for Aphasia

SK
Overseen BySwathi Kiran, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Boston University Charles River Campus
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The objective of this study is to apply state-of-the art brain imaging approaches to evaluate new hypotheses about the contributions of core linguistic vs. domain-general executive systems to language processing and recovery in patients with varying degrees of linguistic impairment. Specifically, the investigators will first characterize the degree to which standard language assessments tax the domain-general Multiple Demand (MD) network (Aim 1). And then systematically investigate the causal contributions of the language and the MD networks to language processing and aphasia recovery in patients of varying severity (Aims 2 and 3).

Who Is on the Research Team?

SK

Swathi Kiran, PhD

Principal Investigator

BU Charles River Campus, Center for Brain Recovery

EF

Evelina Fedorenko, PhD

Principal Investigator

Massachusetts Institute of Technology

Are You a Good Fit for This Trial?

This trial is for people with aphasia, a language disorder often caused by brain injury or stroke. Participants will have varying levels of language difficulties. Specific inclusion and exclusion criteria are not detailed.

Inclusion Criteria

A family member or caregiver available to assist in study setup and in communicating with study staff
At least 12 weeks post-stroke at time of study enrolment
Premorbid fluency in English
See 1 more

Exclusion Criteria

Severe uncorrected vision and/or hearing problems likely to impact study participation
Comorbid learning or language disorder diagnosed prior to stroke or as a child
I have had a stroke with symptoms before my most recent stroke.
See 2 more

What Are the Treatments Tested in This Trial?

Interventions

  • Constant Therapy program

Trial Overview

The study tests the Constant Therapy program, which uses exercises to help improve language skills in people with aphasia. Researchers use advanced brain scans to see how different parts of the brain support recovery.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Immediate treatmentExperimental Treatment1 Intervention
Group II: Delayed treatmentActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Boston University Charles River Campus

Lead Sponsor

Trials
125
Recruited
14,100+

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborator

Trials
377
Recruited
190,000+