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Health Behavior Change Intervention for Alzheimer's Disease

(TEACH Trial)

LK
JD
Overseen ByJennifer Davis, Ph.D.
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Rhode Island Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This Stage II behavioral intervention development project will examine the efficacy of a multi-domain health behavior intervention for primary prevention of Alzheimer's disease and related dementias (ADRD) in middle age.

Are You a Good Fit for This Trial?

This trial is for middle-aged adults who may be at risk for Alzheimer's disease or related dementias, possibly due to factors like diabetes, high blood pressure, or other health concerns. Specific inclusion and exclusion criteria are not detailed.

Inclusion Criteria

I am between 40 and 69 years old.
Normal cognition (Telephone Interview for Cognitive Status-Modified > 32)
Participants must have suboptimal engagement in at least one core health behavior: Diet Mediterranean Diet Adherence Screener (MEDAS) total score < 10, Physical activity <120 minutes of moderate-intensity or <60 minutes of vigorous-intensity physical activity per week, Sleep <=7 hours of sleep per night (past-week average)
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Exclusion Criteria

I have been diagnosed with a mild or major neurocognitive disorder.
Current enrollment in an ADRD prevention clinical trial
I do not have severe disabilities or unstable health that limit my activity.
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What Are the Treatments Tested in This Trial?

Interventions

  • Basic health education
  • TEACH

Trial Overview

The study compares a tailored multi-domain health behavior program (TEACH) with basic health education to see which better helps prevent Alzheimer's and related conditions in midlife adults.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: ExperimentalExperimental Treatment1 Intervention
Group II: ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Rhode Island Hospital

Lead Sponsor

Trials
275
Recruited
71,400+

The Miriam Hospital

Collaborator

Trials
252
Recruited
39,200+

Brown University

Collaborator

Trials
480
Recruited
724,000+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+

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