Virtual Music Therapy for Alzheimer's Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether virtual music therapy can improve memory, mood, and thinking skills in people with mild memory issues due to Alzheimer's Disease. Participants will engage in two 30-minute music sessions each week for eight weeks, all conducted online. The study examines changes in memory, anxiety, and quality of life, with some participants also undergoing brain scans. This trial suits those with mild memory problems linked to Alzheimer's who can participate in online sessions. As an unphased trial, it offers a unique opportunity to explore innovative therapy options that could enhance quality of life.
Do I need to stop my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What prior data suggests that this virtual music therapy is safe for Alzheimer's patients?
Research has shown that music therapy is generally safe for people with Alzheimer's Disease. Studies suggest it can improve mood and memory without harmful side effects. One review found that music therapy helps with symptoms like anxiety and agitation. Another study noted that music therapy might help preserve musical memory, even when other memories fade. These findings indicate that participants in virtual music therapy sessions can expect a safe experience with no significant risks.12345
Why are researchers excited about this trial?
Virtual Music Therapy for Alzheimer's Disease is unique because it offers a non-drug approach that can be accessed conveniently at home through virtual sessions. Unlike traditional treatments that primarily involve medications like cholinesterase inhibitors or memantine, this therapy aims to engage patients through music, potentially enhancing mood and cognitive function. Researchers are excited about this treatment because it could provide a safe, enjoyable, and easily accessible way to support patients and caregivers, possibly improving quality of life without the side effects associated with many standard medications.
What evidence suggests that virtual music therapy is effective for Alzheimer's Disease?
Research has shown that virtual music therapy, which participants in this trial will receive, can benefit people with Alzheimer's Disease (AD). Studies have found that music therapy can slow memory loss, particularly in recalling personal experiences and events. It also appears to enhance the ability to think and move simultaneously, as well as skills needed for planning and focusing. Additionally, music therapy has been linked to reduced agitation and depression in people with dementia. Music seems to uniquely reach parts of the brain that remain active even when other areas are affected by Alzheimer's.56789
Who Is on the Research Team?
Alexander Pantelyat, MD
Principal Investigator
Department of Neurology, Johns Hopkins School of Medicine
Are You a Good Fit for This Trial?
This trial is for adults aged 18-89 with mild cognitive impairment or early Alzheimer's Disease, as indicated by specific scores on a cognitive assessment test (MoCA). It excludes those who've had significant head trauma, are claustrophobic to the extent that they can't undergo MRI scans, have medical devices or metal in their body that interfere with MRI technology.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive reminiscence-targeted virtual music therapy sessions twice a week for 8 weeks
Follow-up
Participants are monitored for changes in cognitive, anxiety, quality of life, and autobiographical memory levels, as well as brain activation patterns using fMRI
What Are the Treatments Tested in This Trial?
Interventions
- Virtual Music Therapy
Virtual Music Therapy is already approved in United States, European Union, China, Japan for the following indications:
- Alzheimer's Disease
- Mild Cognitive Impairment
- Alzheimer's Disease
- Dementia
- Alzheimer's Disease
- Cognitive Impairment
- Alzheimer's Disease
- Dementia
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johns Hopkins University
Lead Sponsor