Exercise for Pain
(PAIN Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how various types of moderate-intensity exercise, such as strength and aerobic workouts, affect pain in individuals with different athletic backgrounds. It compares pain experiences among former competitive athletes, current master's athletes, and nonathletes. Participants will engage in both strength and aerobic exercises across three sessions, with pain assessments conducted before and after each workout. Suitable candidates include individuals aged 35 to 65 who are former athletes, current master's athletes, or have not participated in competitive sports in the last five years. As an unphased trial, this study allows participants to contribute to understanding pain management through exercise, potentially informing future exercise recommendations.
Do I need to stop my current medications for the trial?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are taking heart rate lowering medications like beta blockers.
What prior data suggests that these exercise interventions are safe for participants?
Research has shown that both moderate aerobic exercise and strength training are generally safe for reducing pain. Studies have found that aerobic exercise can raise the body's pain threshold, leading to less pain after exercising. This effect is particularly beneficial for individuals with muscle and joint pain, as aerobic exercise often reduces their pain levels. Similarly, strength training is safe and rarely causes issues. It can also enhance bodily function and lessen pain severity.
In summary, both types of exercise are well-tolerated and have relieved pain without serious side effects.12345Why are researchers excited about this trial?
Researchers are excited about these exercise interventions for pain management because they offer a drug-free, non-invasive option that could provide relief without the side effects associated with medications like NSAIDs or opioids. Unlike typical treatments, which often focus on pain relief through pharmaceuticals, these moderate-intensity aerobic and strength exercises aim to enhance the body's natural pain management systems and improve overall physical function. By engaging former athletes, master's athletes, and nonathletes, researchers hope to understand how different levels of prior physical activity impact the effectiveness of these exercise interventions, potentially leading to personalized pain management strategies.
What evidence suggests that this trial's exercise interventions could be effective for pain management?
This trial will evaluate the effects of moderate-intensity aerobic and strength exercises on pain management. Research has shown that moderate-intensity aerobic exercise can reduce pain perception. Several studies have found that individuals with conditions like fibromyalgia experience less pain after regular aerobic exercise. For example, one study reported a significant drop in pain levels. Similarly, moderate-intensity strength exercises are linked to pain relief and improved movement. Reviews suggest that consistent practice of these exercises can noticeably decrease pain. Both aerobic and strength exercises appear promising for managing pain across various groups. Participants in this trial will engage in both types of exercise interventions.678910
Who Is on the Research Team?
Jacob J Capin, DPT, PhD
Principal Investigator
Marquette University
Are You a Good Fit for This Trial?
This trial is for men and women aged 35-65 who are current master's athletes, former competitive athletes, or non-athletes. Participants must be able to safely exercise based on a screening questionnaire. People with certain heart conditions, chronic pain syndromes like fibromyalgia, recent serious illness, pregnancy, or other safety concerns cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Testing
Baseline testing including assessments of strength, cardiorespiratory fitness, and pain
Strength Exercise Intervention
Participants undergo moderate-intensity strength training exercise with pain assessments before and after
Aerobic Exercise Intervention
Participants undergo moderate-intensity aerobic exercise with pain assessments before and after
Follow-up
Participants are monitored for changes in pain response and lifestyle behaviors
What Are the Treatments Tested in This Trial?
Interventions
- Moderate-Intensity Aerobic Exercise Intervention
- Moderate-Intensity Strength Exercise Intervention
Trial Overview
The study compares how moderate-intensity strength and aerobic exercises affect pain in former athletes, master's athletes, and nonathletes. Each participant tries both types of exercise in random order across separate sessions (crossover design).
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Active Control
Former competitive athletes will complete baseline testing as well as two separate experimental conditions in randomized condition order: 1) moderate-intensity strength exercise intervention; and 2) moderate-intensity aerobic exercise intervention.
Master's Athletes will complete baseline testing as well as two separate experimental conditions in randomized condition order: 1) moderate-intensity strength exercise intervention; and 2) moderate-intensity aerobic exercise intervention.
Nonathlete Controls will complete baseline testing as well as two separate experimental conditions in randomized condition order: 1) moderate-intensity strength exercise intervention; and 2) moderate-intensity aerobic exercise intervention.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Marquette University
Lead Sponsor
Citations
The effectiveness of aerobic exercise for pain management in ...
Overall, our results indicate that aerobic exercise is effective for pain management in patients with fibromyalgia.
The effectiveness of different aerobic exercises to improve ...
Results demonstrated pain intensity improved in both groups at six months (EG vs CG = 21.7% vs 14.8%) and 12 months (EG vs CG = 10% vs 8.2%), ...
The effectiveness of aerobic exercise on pain and disability in ...
Aerobic exercise (AE) was shown to be equally effective as other active treatment modalities in reducing neck pain, although the overall ...
Aerobic Exercise Attenuates Pain Sensitivity: An Event- ...
Moderate-intensity aerobic exercise effectively reduced the sensitivity to various painful stimuli, and low-intensity aerobic exercise selectively inhibited ...
Pain intensity and pain sensitivity are not increased by a ...
This study found that a single session of 15 min of high-intensity interval aerobic exercise does not increase pain intensity nor pain sensitivity compared to ...
Physical activity and exercise for chronic pain in adults - PMC
Exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and ...
Hot Topic | Exercise as a Pain Management Modality
By dulling pain, exercise may reduce the need for additional, more potent pain management interventions, open the door to meaningful movement, ...
Does aerobic exercise effect pain sensitisation in individuals ...
All 11 studies found that aerobic exercise increased pressure pain thresholds or decreased pain ratings in those with musculoskeletal pain.
Acute aerobic exercise intensity does not modulate pain ...
Overall, high-intensity aerobic exercise did not reduce pain as compared to low-intensity aerobic exercise.
How is Aerobic Exercise Compared to Localized Pain ...
Previous literature found positive results in favor of aerobic exercise for pain relief. However, none of them included patients with jaw and neck-related ...
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