Restylane Injectables for Cosmetic Use

This trial explores how different types of Restylane, a popular facial filler, distribute and remain in place after cosmetic injection. Researchers focus on how well these fillers integrate with facial tissues and whether they migrate from the original injection site. The trial suits individuals with noticeable facial volume loss or contour issues who haven't used facial fillers in the past 18 months. Participants must agree to follow the study's rules, including avoiding other facial procedures during the trial. As an unphased trial, this study allows participants to contribute to valuable research on facial fillers and their effects.

The trial does not specify if you need to stop taking your current medications, but you should avoid certain treatments like blood thinners and NSAIDs (non-steroidal anti-inflammatory drugs) two weeks before treatment. It's best to discuss your specific medications with the trial team.

Research has shown that Restylane injections are generally safe and have been used worldwide for over 20 years. U.S. studies have found these fillers safe for most people.

However, some risks exist. In rare cases, vision problems, including blindness, have occurred when fillers were injected into areas like the nose. Trained professionals should perform injections to help reduce these risks.

Restylane injectables are unique because they utilize hyaluronic acid, a natural substance found in the body, to enhance facial volume and smooth out wrinkles. Unlike other treatments that might use synthetic fillers or require surgical intervention, Restylane offers a minimally invasive option with immediate results and minimal downtime. Researchers are excited about Restylane because its biocompatibility reduces the risk of adverse reactions, and its effects can be long-lasting, providing natural-looking improvements in facial aesthetics.

Research has shown that Restylane fillers effectively refresh the face, add volume, and improve shape. For instance, one study found that 82% of participants saw an improvement in their appearance up to 9 months after receiving Restylane injections. Another study demonstrated that all participants using Restylane for cheek fillers perceived the results as natural. Restylane is also recognized for its safety and effectiveness, particularly in reducing smile lines. These fillers enhance facial features and create soft contours while maintaining natural expressions.¹⁶⁷⁸⁹