Brain Stimulation for Age-Related Memory Decline

This trial aims to determine if brain stimulation can help with memory decline associated with aging. It uses high-definition transcranial electrical current stimulation, which sends small electrical currents to the brain. Participants will receive either actual brain stimulation or a sham version to assess any real effects. Suitable candidates are individuals aged 68-80 who have noticed memory problems but do not have major neurological issues or head injuries. As an unphased trial, this study allows participants to contribute to groundbreaking research on memory improvement techniques.

If you are taking any psychoactive medication (drugs that affect your mind, emotions, or behavior), you will need to stop taking them to participate in this trial.

Research has shown that high-definition transcranial electrical current stimulation (HD-tDCS) is generally safe. Studies have found that patients tolerate it well. For example, a review found that HD-tDCS can improve memory in people with Alzheimer's disease without causing major side effects. Another study demonstrated its effectiveness in addressing sleep problems in people with chronic insomnia, again with no serious negative effects reported. Overall, evidence suggests that HD-tDCS is a safe option for enhancing brain functions.¹²³⁴⁵

Unlike traditional treatments for age-related memory decline, which often involve medication or cognitive therapy, high definition transcranial electrical current stimulation (HD-tDCS) offers a non-invasive way to potentially enhance brain function. This technique uses precise electrical currents to stimulate specific brain areas, aiming to improve memory by directly influencing neural activity. Researchers are excited because HD-tDCS might offer quicker results with fewer side effects compared to current options, potentially leading to safer and more effective management of memory decline.

Studies have shown that transcranial direct current stimulation (tDCS) can improve thinking skills in older adults. Research indicates that this treatment enhances memory and word recall. A review of several studies found that combining tDCS with brain exercises is more effective than exercises alone, resulting in better and longer-lasting improvements in thinking skills. One study demonstrated that participants experienced improved learning and memory recall after receiving tDCS. These findings suggest that this brain stimulation may help reduce age-related memory decline. In this trial, participants will receive either active stimulation using high-definition transcranial electrical current stimulation or a sham stimulation to evaluate its effectiveness in addressing age-related memory decline.³⁶⁷⁸⁹