DHEA vs Estradiol for Menopause
What You Need to Know Before You Apply
What is the purpose of this trial?
This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause. These symptoms may include vaginal dryness, discomfort, painful intercourse, or urinary problems and can affect quality of life and sexual health. Women who choose to participate will be randomly assigned to use one of the two treatments for a set period of time. Participants will complete questionnaires about their symptoms and sexual health and have simple vaginal testing at the beginning and end of the study. The goal of this research is to better understand how these treatments affect vaginal health and sexual function so healthcare providers can make informed treatment decisions and improve care for postmenopausal women.
Who Is on the Research Team?
Molloy Shaida
Principal Investigator
University of Arizona
Are You a Good Fit for This Trial?
This trial is for women ages 40-90 who are peri- or post-menopausal and have vaginal or urinary symptoms like dryness, discomfort, or pain during sex. Participants must be able to use vaginal treatments, speak English, and give informed consent.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- DHEA ovals
- Estradiol 0.01% Vag Cream
Trial Overview
The study compares two vaginal treatments—DHEA ovules versus low-dose estradiol cream—to see which works better for relieving menopause-related vaginal and urinary symptoms. Women are randomly assigned to one of the two treatments.
How Is the Trial Designed?
2
Treatment groups
Active Control
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Arizona
Lead Sponsor
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