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Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)

(CORTISS Trial)

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FS
Overseen ByFrancesca Sarzetto, MD, MSc
Age: 18+
Sex: Any
Trial Phase: Phase 4
Sponsor: Igor Wilderman. MD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between injections with steroids and local anesthetics, to optimize this treatment that is currently not standardized. The investigators will compare retrospectively and prospectively the efficacy of different injections in the same patients, using mainly a parameter called integral of pain relief, which combines the percentage of pain relief provided by a treatment and its duration over time, as well as improvements in functionality.

Who Is on the Research Team?

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Igor Wilderman, MD

Principal Investigator

Canadian Centre for Clinical Trials

Are You a Good Fit for This Trial?

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

4

Treatment groups

Active Control

Group I: Spinal steroid injections with methylprednisoloneActive Control1 Intervention
Group II: Spinal steroid injections with betamethasoneActive Control1 Intervention
Group III: Spinal steroid injections with dexamethasoneActive Control1 Intervention
Group IV: Spinal steroid injections with triamcinoloneActive Control1 Intervention

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Who Is Running the Clinical Trial?

Igor Wilderman. MD

Lead Sponsor

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