200 Participants NeededMy employer runs this trial

mRNA Vaccine for Flu

Recruiting at 3 trial locations
MW
Overseen ByModerna WeCare Team
Age: 65+
Sex: Any
Trial Phase: Phase 4
Sponsor: ModernaTX, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate the immunogenicity and safety of updated strain-containing compositions of the mRNA-1010 vaccines within the current epidemiological environment.

Are You a Good Fit for This Trial?

This trial is for adults who can give informed consent and, if female, are not able to become pregnant. Participants should be generally healthy and willing to follow study rules.

Inclusion Criteria

I am able to understand and sign the consent form for this study.
I am a woman who cannot become pregnant.
This is a key eligibility criterion for the study.

What Are the Treatments Tested in This Trial?

Interventions

  • mRNA-1010

Trial Overview

The study compares an updated mRNA flu vaccine (mRNA-1010) with a standard high-dose seasonal flu shot. It looks at how well each vaccine works and their safety in the current flu season.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: mRNA-1010 Influenza Strain-containing Composition (2026- 2027)Experimental Treatment1 Intervention
Group II: Licensed High-Dose Seasonal Influenza VaccineActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

ModernaTX, Inc.

Lead Sponsor

Trials
127
Recruited
66,790,000+

Dr. Stephen Hoge

ModernaTX, Inc.

Chief Medical Officer

MD from Harvard Medical School

Stéphane Bancel profile image

Stéphane Bancel

ModernaTX, Inc.

Chief Executive Officer since 2011

MBA from Harvard Business School, MSc in Engineering from École Centrale Paris