Corticosteroid for Diabetic Macular Edema
What You Need to Know Before You Apply
What is the purpose of this trial?
Our current goals include confirming inflammation mediators are biomarkers of DR and DME
The Aim of this project is to measure aqueous PGE2 and inflammatory cytokines before and after treatment of DME with intravitreal corticosteroid injections.
We want to continue the study for one more year as our initial data analysis from the original INSPIRE study shows a possible direct correlation between aqueous biomarkers and DME. We propose treating the DME with corticosteroid to assess the effect upon the intraocular cytokines with inflammation is suppressed.
Are You a Good Fit for This Trial?
This trial is for people with diabetic macular edema (DME), a complication of diabetes that affects the eyes. Participants should have DME and not have conditions or treatments that would interfere with the study, as determined by the researchers.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Intravitreal dexamethasone implant
Trial Overview
The study tests an injection of dexamethasone (a corticosteroid) directly into the eye to see how it affects inflammation markers in patients with DME. Researchers will measure these markers before and after treatment.
How Is the Trial Designed?
1
Treatment groups
Active Control
Find a Clinic Near You
Who Is Running the Clinical Trial?
Vanderbilt University Medical Center
Lead Sponsor
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