18F-FDG PET/CT Imaging for Pericarditis
What You Need to Know Before You Apply
What is the purpose of this trial?
The pericardium is a thin, double-layered sac around the heart that helps reduce friction as the heart moves. When this sac gets inflamed, it is called pericarditis, which can cause serious health problems and even be life-threatening. Pericarditis often comes back after the first episode. About 10-30% of people will have it again, and half of those will have it multiple times. Although there are treatments available, they are costly and not often used because we can't predict who best to use them on. Finding a way to predict which patients would benefit from these treatments could help reduce the burden on patients and the healthcare system.
This study will use a test called an 18F-FDG PET/CT with CTA Scan (18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) with computer tomography angiography (CTA)) to measure inflammation in the pericardium.
The purpose of the study is to create easy-to-use tools for doctors to identify people at high risk of pericarditis coming back, so they can get advanced treatment early. This study will help fill knowledge gaps about key predictors like clinical signs, blood tests, and imaging results.
Are You a Good Fit for This Trial?
This study is for adults (18 or older) who have had at least two episodes of pericarditis, diagnosed by standard criteria. Participants must be able to give informed consent.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Trial Overview
The trial uses an imaging test called 18F-FDG PET/CT with CTA to measure inflammation around the heart in people with recurrent pericarditis. The goal is to find ways to predict who might have future flare-ups.
How Is the Trial Designed?
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Treatment groups
Experimental Treatment
This is a single arm study. Participants enrolled will complete blood and imaging tests.
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Who Is Running the Clinical Trial?
Ottawa Heart Institute Research Corporation
Lead Sponsor
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