Cognitive Behavioral Therapy for Depression and Suicide Prevention

This trial explores the effectiveness of two self-guided online cognitive behavioral therapy (CBT) courses for veterans. One course targets reducing symptoms of depression, while the other addresses past suicidal thoughts and behaviors. Veterans in Colorado, New York, Montana, Texas, or Utah who have accessed VA care and meet specific mental health criteria may qualify. Participants need reliable internet and a computer or tablet to access the therapy. The study aims to discover new ways to support mental health through accessible online resources. As a Phase 2 trial, this research measures the treatment's effectiveness in an initial, smaller group, offering veterans a chance to contribute to potentially impactful mental health solutions.

The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your healthcare provider.

Research has shown that computerized cognitive behavioral therapy (CBT) is generally safe and well-received by patients. Studies have found that online CBT effectively lessens symptoms of depression and reduces thoughts of self-harm. Specifically, evidence indicates that internet-based CBT significantly decreases suicidal thoughts.

Regarding safety, existing studies have reported no major negative effects. This indicates that people using these online programs did not experience serious side effects. Research on computerized CBT for reducing depression and anxiety further supports its safety for these issues.

Most treatments for depression and suicide prevention, like traditional cognitive behavioral therapy (CBT), involve face-to-face sessions with a therapist. However, the computerized CBT being studied is unique because it's delivered online, making it accessible to people who might not have easy access to in-person therapy due to location, mobility, or time constraints. Researchers are excited about this treatment because it offers the potential for greater reach and flexibility, allowing more people to get help on their own schedule. Additionally, the digital format can be cost-effective, potentially reducing the financial barriers to receiving mental health care.

Research has shown that computerized cognitive behavioral therapy (CBT), which participants in this trial will receive, effectively treats depression and suicidal thoughts. Studies have found that online CBT can greatly reduce suicidal thoughts and attempts. One study found that digital CBT works well for people of all ages and backgrounds. Another study confirmed that computerized CBT is as effective as traditional in-person therapy for treating depression. These findings suggest that CBT delivered online can be a powerful tool for improving mental health.¹²⁴⁶⁷