Exercise Classes for Colorectal Cancer

(ACE-Dose-CRC Trial)

AF
Overseen ByAude-Marie Foucaut, PhD
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: University of Calgary
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this pilot randomized, wait-list controlled study is to evaluate the effects of exercise dose in terms of frequency (1 vs. 2 days per week) in individuals on systemic treatment for colorectal cancer. The impact on the individual (physical function, quality of life, fatigue and other patient reported outcomes) as well as on health care utilization (cost to deliver, cost to individuals, savings and impact to the health care system) will be evaluated. In addition, assessments of immunological markers to better understand the biological impact of exercise dose on immunological markers will be explored.

Who Is on the Research Team?

SN

S. Nicole Culos-Reed, PhD

Principal Investigator

University of Calgary

Are You a Good Fit for This Trial?

This trial is for people currently receiving systemic treatment for colorectal cancer. Participants should be able to safely take part in group exercise classes, as determined by the study team.

Inclusion Criteria

Cleared for exercise (PAR-Q+)
Able to attend scheduled sessions
Able to provide informed written consent in English
See 3 more

Exclusion Criteria

I have finished my post-surgery treatment for colorectal cancer.
I have high blood pressure that is not well controlled.
Contraindication to needles/venipuncture
See 4 more

What Are the Treatments Tested in This Trial?

Interventions

  • Group Exercise Classes

Trial Overview

The study compares two different amounts of supervised group exercise—either once or twice a week—to see how often exercising helps with physical function, quality of life, fatigue, and health care costs. Participants are randomly assigned to one of the groups.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Active Control

Group I: Once/week exercise session for 12 weeks (Arm 1)Experimental Treatment1 Intervention
Group II: Twice/week exercise session for 12 weeks (Arm 2)Active Control1 Intervention
Group III: Control-waitlisted group (Arm 3)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials
827
Recruited
902,000+

Arthur J.E. Child Comprehensive Cancer Centre

Collaborator

Trials
1
Recruited
100+