Pentadecanoic Acid for Healthy Aging

JR
SR
Overseen ByStephanie Recker
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine whether pentadecanoic acid (C15:0), a type of fatty acid, can enhance red blood cell health and reduce biological age in healthy adults over 55. Participants will receive either 200 mg or 300 mg of C15:0, or a placebo, daily for 12 weeks. Researchers will also assess inflammation, fatigue, sleep quality, and overall quality of life. This trial suits individuals over 55 who are healthy, on a stable medication plan, and can maintain consistent lifestyle habits. As a Phase 2 trial, this research measures the treatment's effectiveness in an initial, smaller group, allowing participants to contribute to significant findings.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that pentadecanoic acid (C15:0) is generally safe for humans. This natural fatty acid occurs in foods like dairy. Studies suggest it may support heart health and metabolism. Previous research involving people has not reported any major side effects. Since this trial is in the second phase, serious safety issues are unlikely, as earlier studies would have identified them. Overall, current evidence indicates that pentadecanoic acid is a safe choice.12345

Why are researchers excited about this trial's treatments?

Unlike the standard of care for healthy aging, which often includes lifestyle changes, supplements, and medications aimed at managing symptoms, Pentadecanoic Acid offers a unique approach by utilizing a naturally occurring fatty acid. Researchers are excited about this treatment because it introduces a novel active ingredient, C15:0, which may support cellular health and longevity. This fatty acid has the potential to enhance overall well-being at a cellular level, potentially providing a more foundational solution to healthy aging than current options.

What evidence suggests that pentadecanoic acid could be an effective treatment for healthy aging?

Research has shown that pentadecanoic acid, a type of fatty acid, may help maintain cell health as people age. Early findings suggest it supports healthy red blood cells, potentially improving overall cell function. Some studies have found a link between higher levels of this fatty acid and better heart health, indicating it might help maintain health during aging. However, more research is needed to confirm these benefits specifically for older adults. This trial will evaluate the effects of pentadecanoic acid at different dosages, with some participants receiving 200 mg/day and others 300 mg/day, while a separate group will receive a placebo. Overall, evidence suggests that pentadecanoic acid has promising potential for supporting healthy aging.678910

Who Is on the Research Team?

BB

Bruce Brown

Principal Investigator

ReCellience15, Inc

Are You a Good Fit for This Trial?

This trial is for healthy adults aged 55 and older. Participants should not have serious health conditions that could interfere with the study or its results.

Inclusion Criteria

Willing and able to agree to the requirements of this study, be willing to give voluntary consent, be able to understand and read the questionnaires, and carry out all study-related procedures
Willing and able to fast overnight (approximately 10 hours)
Agree to follow the restrictions on concomitant treatments
See 8 more

Exclusion Criteria

I have had major surgery in the last 3 months or plan to have one during the study.
Individuals who are pregnant, intending to breastfeed, or intending to conceive at the time of consent and during the study, or demonstrate a positive pregnancy test
Recent blood donation (<8 weeks)
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks
1 visit (in-person)

Treatment

Participants receive daily supplementation of pentadecanoic acid or placebo for 12 weeks

12 weeks
Baseline/randomization visit, Week 6 interim visit, Week 12 end-of-study visit

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Pentadecanoic Acid

Trial Overview

The study tests daily supplements of pentadecanoic acid (C15:0) at two different doses versus a placebo over about 12 weeks, to see if it improves red blood cell health and slows biological aging in older adults. The design is randomized and double-blind.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Placebo Group

Group I: Pentadecanoic Acid (300 mg/day)Experimental Treatment1 Intervention
Group II: Pentadecanoic Acid (200 mg/day)Experimental Treatment1 Intervention
Group III: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

ReCellience15, Inc

Lead Sponsor

Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Collaborator

Trials
40
Recruited
2,400+

Citations

1.

outcomes.com

outcomes.com/

Outcomes | Healthcare Solutions for Pharmacy, Pharma, and ...

The Outcomes platform is the ideal solution for gaining insight across the entire treatment journey. Gain access to all the data you need to improve medication ...

2.

secure.outcomesmtm.com

secure.outcomesmtm.com/

Outcomes Login

No information is available for this page.

3.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/31422062/

Cardiovascular, mortality, and kidney outcomes with GLP-1 ...

Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of ...

Child Welfare Outcomes

These reports include data from the Adoption and Foster Care Analysis and Reporting System (AFCARS) and the National Child Abuse and Neglect Data System (NCANDS) ...

OUTCOME Definition & Meaning

The meaning of OUTCOME is something that follows as a result or consequence. How to use outcome in a sentence.

Pentadecanoic Acid - Health Benefits and Risks - Oasis

Learn about Pentadecanoic Acid: health benefits, risks, and where it appears in products. Science-backed ingredient analysis from Oasis.

Is Fatty Acid C15:0 Your New Health Ally?

Pentadecanoic acid is an essential fatty acid like omega 3 and omega 6, meaning that the body cannot make it on its own and we need to consume ...

pentadecanoic acid. A saturated fatty acid found naturally ...

C15:0 is a once-in-a-century essential fatty acid that protects our cells and supports healthy aging at every stage of life. Backed by 100+ ...

Pentadecanoic Acid (C15:0), an Essential Fatty ...

Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds.

Pentadecanoic Acid (C15:0) in Supplements & Functional ...

Pentadecanoic acid C15, targeting middle-aged and elderly populations for cardiac protection, liver support, or blood glucose regulation.