Pentadecanoic Acid for Healthy Aging

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SR
Overseen ByStephanie Recker
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: ReCellience15, Inc
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy adults aged 55 years and older. A total of 93 participants will be randomized to receive 200 mg of C15:0, 300 mg of C15:0, or placebo daily for approximately 12 weeks. The primary objective is to assess the effect of C15:0 on red blood cell distribution width (RDW-CV), a marker of RBC health, compared with placebo. Secondary outcomes include measures of inflammation, hematologic and iron metabolism markers, circulating C15:0 levels, biological age-related biomarkers, sleep quality, fatigue, energy, and health-related quality of life. Safety and tolerability will also be evaluated throughout the study.

Who Is on the Research Team?

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Bruce Brown

Principal Investigator

ReCellience15, Inc

Are You a Good Fit for This Trial?

This trial is for healthy adults aged 55 and older. Participants should not have serious health conditions that could interfere with the study or its results.

Inclusion Criteria

Willing and able to agree to the requirements of this study, be willing to give voluntary consent, be able to understand and read the questionnaires, and carry out all study-related procedures
Willing and able to fast overnight (approximately 10 hours)
Agree to follow the restrictions on concomitant treatments
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Exclusion Criteria

I have had major surgery in the last 3 months or plan to have one during the study.
Individuals who are pregnant, intending to breastfeed, or intending to conceive at the time of consent and during the study, or demonstrate a positive pregnancy test
Recent blood donation (<8 weeks)
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What Are the Treatments Tested in This Trial?

Interventions

  • Pentadecanoic Acid

Trial Overview

The study tests daily supplements of pentadecanoic acid (C15:0) at two different doses versus a placebo over about 12 weeks, to see if it improves red blood cell health and slows biological aging in older adults. The design is randomized and double-blind.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Placebo Group

Group I: Pentadecanoic Acid (300 mg/day)Experimental Treatment1 Intervention
Group II: Pentadecanoic Acid (200 mg/day)Experimental Treatment1 Intervention
Group III: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

ReCellience15, Inc

Lead Sponsor

Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Collaborator

Trials
40
Recruited
2,400+