YCANTH for Warts

(COVE-5 Trial)

Not yet recruiting at 3 trial locations
PM
Overseen ByProject Manager
Age: Any Age
Sex: Any
Trial Phase: Phase 2
Sponsor: Verrica Pharmaceuticals Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This is a Phase 2, open-label study (Study VP-CW-304; referred to as COVE-5 \[Cantharidin and Occlusion in Verruca Epithelium 5\]) to evaluate the safety and systemic exposure of YCANTH (VP-102) following a single 24-hour dermal application in subjects with common warts.

Are You a Good Fit for This Trial?

This trial is for people who have common warts, including those around the nails or on the feet. Participants should be generally healthy and able to follow study instructions. Specific inclusion and exclusion details are not provided.

Inclusion Criteria

Agree to refrain from swimming, bathing, or prolonged immersion in water until study drug is removed after treatment
Immunocompetent
Agree to required blood draws
See 6 more

Exclusion Criteria

I am allergic to the study drug or its ingredients.
Have chronic or acute medical conditions that may interfere with study results or place subject at undue risk
Have clinically significant medical, psychiatric, or emotional conditions that may compromise safety or data quality
See 12 more

What Are the Treatments Tested in This Trial?

Interventions

  • VP-102

Trial Overview

The study tests a single application of YCANTH (VP-102), a topical treatment applied to warts for 24 hours, to see how safe it is and how much of the drug enters the body. The trial does not use a placebo group.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: VP-102Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Verrica Pharmaceuticals Inc.

Lead Sponsor

Trials
6
Recruited
810+

Veeva Systems

Industry Sponsor

Trials
7
Recruited
3,400+

Medidata Solutions

Industry Sponsor

Trials
25
Recruited
25,600+

Allucent (US) LLC

Collaborator

Myonex LLC

Collaborator