300 Participants NeededMy employer runs this trial

Olatorepatide for Hidradenitis Suppurativa

Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Regeneron Pharmaceuticals
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will test an experimental Regeneron drug called olatorepatide ("study drug") to see if it can help treat Hidradenitis Suppurativa (HS).

In this study, olatorepatide is being tested in people with HS and living with overweight or obesity to see if it helps improve their HS symptoms and quality of life and helps support weight loss.

The study is looking at:

* What side effects olatorepatide might cause

* How well olatorepatide works

* How much olatorepatide is in the blood at different times

* If the body makes antibodies to olatorepatide, which may cause olatorepatide to not work as well

Who Is on the Research Team?

CT

Clinical Trial Management

Principal Investigator

Regeneron Pharmaceuticals

Are You a Good Fit for This Trial?

This trial is for adults who have had moderate to severe hidradenitis suppurativa (HS) for at least 6 months, with HS lesions in at least 2 body areas and a BMI of 27 or higher. Participants must agree to use daily antiseptics on affected skin.

Inclusion Criteria

I have moderate to severe HS with at least 5 inflamed lesions at both recent visits.
My BMI is 27 or higher.
This is a key eligibility criterion for the study.
See 4 more

What Are the Treatments Tested in This Trial?

Interventions

  • Olatorepatide

Trial Overview

The study compares the experimental drug olatorepatide to a placebo in people with HS and overweight or obesity. It aims to see if olatorepatide improves HS symptoms, quality of life, and supports weight loss.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: OlatorepatideExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Regeneron Pharmaceuticals

Lead Sponsor

Trials
690
Recruited
948,000+
Founded
1988
Headquarters
Tarrytown, USA
Known For
Precision medicine
Top Products
Dupixent, EYLEA, Libtayo, Praluent
Leonard Schleifer profile image

Leonard Schleifer

Regeneron Pharmaceuticals

Chief Executive Officer since 1988

MD and PhD in Medicine

George Yancopoulos profile image

George Yancopoulos

Regeneron Pharmaceuticals

Chief Medical Officer since 1997

MD from Harvard Medical School